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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS53
All Species:
21.82
Human Site:
T371
Identified Species:
48
UniProt:
Q5VIR6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VIR6
NP_001121631.1
699
79653
T371
G
C
T
L
T
D
G
T
L
K
K
L
E
S
P
Chimpanzee
Pan troglodytes
XP_001151796
699
79606
T371
G
C
T
L
T
D
G
T
L
K
K
L
E
S
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_868404
697
79456
T371
G
C
T
L
T
D
G
T
L
K
K
L
E
C
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCB4
832
94405
T371
G
C
T
L
T
D
G
T
L
K
K
L
E
S
P
Rat
Rattus norvegicus
NP_001099283
832
94411
T371
G
C
T
L
T
D
G
T
L
K
K
L
E
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513747
831
94249
A370
G
C
T
L
S
D
G
A
P
K
K
L
E
A
P
Chicken
Gallus gallus
Q5ZLD7
831
93687
T370
G
C
T
L
A
D
G
T
V
K
K
P
E
A
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608825
887
99804
P376
G
V
T
L
G
A
Q
P
T
D
K
A
R
V
L
Honey Bee
Apis mellifera
XP_623283
834
95369
D367
G
I
T
L
E
N
L
D
V
G
N
K
K
N
T
Nematode Worm
Caenorhab. elegans
P34561
798
89225
E356
E
K
D
G
I
S
F
E
K
A
I
W
S
V
F
Sea Urchin
Strong. purpuratus
XP_796587
943
107704
G374
G
V
T
L
Q
P
P
G
E
S
S
S
A
G
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
98
N.A.
81.3
80.8
N.A.
76.1
78
N.A.
N.A.
N.A.
31.7
47.7
26.3
48.9
Protein Similarity:
100
100
N.A.
98.5
N.A.
82.9
82.4
N.A.
79.9
80.3
N.A.
N.A.
N.A.
48.7
61.9
44.6
59.6
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
73.3
73.3
N.A.
N.A.
N.A.
26.6
20
0
20
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
86.6
86.6
N.A.
N.A.
N.A.
26.6
46.6
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
10
0
10
0
10
10
19
0
% A
% Cys:
0
64
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
10
0
0
64
0
10
0
10
0
0
0
0
0
% D
% Glu:
10
0
0
0
10
0
0
10
10
0
0
0
64
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% F
% Gly:
91
0
0
10
10
0
64
10
0
10
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
10
64
73
10
10
0
0
% K
% Leu:
0
0
0
91
0
0
10
0
46
0
0
55
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
10
0
0
10
10
% N
% Pro:
0
0
0
0
0
10
10
10
10
0
0
10
0
0
64
% P
% Gln:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
0
10
10
0
0
0
10
10
10
10
37
0
% S
% Thr:
0
0
91
0
46
0
0
55
10
0
0
0
0
0
10
% T
% Val:
0
19
0
0
0
0
0
0
19
0
0
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _