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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS53
All Species:
26.67
Human Site:
T593
Identified Species:
58.67
UniProt:
Q5VIR6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VIR6
NP_001121631.1
699
79653
T593
N
L
T
G
E
M
D
T
F
S
T
V
I
S
S
Chimpanzee
Pan troglodytes
XP_001151796
699
79606
T593
N
L
T
G
E
M
D
T
F
S
T
V
I
S
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_868404
697
79456
T593
N
L
T
G
E
M
D
T
F
S
T
V
I
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCB4
832
94405
T593
N
L
T
G
E
M
D
T
F
S
T
V
I
S
S
Rat
Rattus norvegicus
NP_001099283
832
94411
T593
N
L
T
G
E
M
D
T
F
S
T
V
I
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513747
831
94249
T592
N
L
S
G
E
R
E
T
F
S
T
V
I
T
S
Chicken
Gallus gallus
Q5ZLD7
831
93687
T592
N
L
T
G
E
T
D
T
F
S
I
V
I
S
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608825
887
99804
V590
D
M
S
E
E
K
D
V
F
H
R
I
I
S
N
Honey Bee
Apis mellifera
XP_623283
834
95369
T582
E
E
K
L
R
E
K
T
D
K
C
Y
A
E
K
Nematode Worm
Caenorhab. elegans
P34561
798
89225
I651
S
V
P
S
I
D
S
I
I
N
S
K
P
P
T
Sea Urchin
Strong. purpuratus
XP_796587
943
107704
C598
L
R
K
S
L
R
N
C
L
N
F
R
I
V
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
98
N.A.
81.3
80.8
N.A.
76.1
78
N.A.
N.A.
N.A.
31.7
47.7
26.3
48.9
Protein Similarity:
100
100
N.A.
98.5
N.A.
82.9
82.4
N.A.
79.9
80.3
N.A.
N.A.
N.A.
48.7
61.9
44.6
59.6
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
73.3
80
N.A.
N.A.
N.A.
33.3
6.6
0
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
93.3
86.6
N.A.
N.A.
N.A.
66.6
6.6
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% C
% Asp:
10
0
0
0
0
10
64
0
10
0
0
0
0
0
0
% D
% Glu:
10
10
0
10
73
10
10
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
73
0
10
0
0
0
0
% F
% Gly:
0
0
0
64
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
10
10
0
10
10
82
0
0
% I
% Lys:
0
0
19
0
0
10
10
0
0
10
0
10
0
0
10
% K
% Leu:
10
64
0
10
10
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
10
0
0
0
46
0
0
0
0
0
0
0
0
0
% M
% Asn:
64
0
0
0
0
0
10
0
0
19
0
0
0
0
19
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
10
19
0
0
0
0
10
10
0
0
0
% R
% Ser:
10
0
19
19
0
0
10
0
0
64
10
0
0
64
55
% S
% Thr:
0
0
55
0
0
10
0
73
0
0
55
0
0
10
10
% T
% Val:
0
10
0
0
0
0
0
10
0
0
0
64
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _