KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS53
All Species:
31.21
Human Site:
Y561
Identified Species:
68.67
UniProt:
Q5VIR6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VIR6
NP_001121631.1
699
79653
Y561
N
I
L
S
T
A
E
Y
C
L
A
T
T
Q
Q
Chimpanzee
Pan troglodytes
XP_001151796
699
79606
Y561
N
I
L
S
T
A
E
Y
C
L
A
T
T
Q
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_868404
697
79456
Y561
G
I
L
S
T
A
E
Y
C
L
A
T
T
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCB4
832
94405
Y561
S
I
L
S
T
A
E
Y
C
L
A
T
T
Q
Q
Rat
Rattus norvegicus
NP_001099283
832
94411
Y561
S
I
L
S
T
A
E
Y
C
L
A
T
T
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513747
831
94249
Y560
S
I
L
S
T
A
E
Y
C
W
A
T
T
Q
Q
Chicken
Gallus gallus
Q5ZLD7
831
93687
Y560
S
I
L
S
T
A
E
Y
C
L
A
T
T
Q
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608825
887
99804
Y558
C
V
L
T
T
G
E
Y
C
L
E
T
V
Q
Q
Honey Bee
Apis mellifera
XP_623283
834
95369
S550
E
G
E
S
T
R
F
S
K
E
E
Q
S
R
I
Nematode Worm
Caenorhab. elegans
P34561
798
89225
R619
K
F
V
G
S
L
F
R
C
R
T
I
S
T
H
Sea Urchin
Strong. purpuratus
XP_796587
943
107704
L566
Q
Y
L
V
C
S
I
L
C
T
A
E
Y
C
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
98
N.A.
81.3
80.8
N.A.
76.1
78
N.A.
N.A.
N.A.
31.7
47.7
26.3
48.9
Protein Similarity:
100
100
N.A.
98.5
N.A.
82.9
82.4
N.A.
79.9
80.3
N.A.
N.A.
N.A.
48.7
61.9
44.6
59.6
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
86.6
93.3
N.A.
N.A.
N.A.
60
13.3
6.6
20
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
93.3
100
N.A.
N.A.
N.A.
73.3
26.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
64
0
0
0
0
73
0
0
0
0
% A
% Cys:
10
0
0
0
10
0
0
0
91
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
10
0
0
0
73
0
0
10
19
10
0
0
0
% E
% Phe:
0
10
0
0
0
0
19
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
10
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
64
0
0
0
0
10
0
0
0
0
10
0
0
10
% I
% Lys:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
82
0
0
10
0
10
0
64
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
10
0
73
73
% Q
% Arg:
0
0
0
0
0
10
0
10
0
10
0
0
0
10
0
% R
% Ser:
37
0
0
73
10
10
0
10
0
0
0
0
19
0
0
% S
% Thr:
0
0
0
10
82
0
0
0
0
10
10
73
64
10
0
% T
% Val:
0
10
10
10
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
73
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _