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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM40A
All Species:
34.55
Human Site:
S440
Identified Species:
69.09
UniProt:
Q5VSL9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VSL9
NP_149079.2
837
95576
S440
I
E
M
F
L
E
S
S
R
S
K
F
I
G
Y
Chimpanzee
Pan troglodytes
XP_524802
813
93885
S416
I
E
M
F
L
E
S
S
R
S
K
F
I
G
Y
Rhesus Macaque
Macaca mulatta
XP_001099183
839
95665
S442
I
E
M
F
L
E
S
S
R
S
K
F
I
G
Y
Dog
Lupus familis
XP_547238
729
83928
K363
H
E
S
I
K
T
L
K
Q
H
K
Y
T
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8C079
837
95566
S440
I
E
M
F
L
E
S
S
R
S
K
F
I
G
Y
Rat
Rattus norvegicus
XP_001068288
837
95591
S440
I
E
M
F
L
E
S
S
R
S
K
F
I
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505396
1036
116496
S429
I
E
M
F
L
E
S
S
R
S
K
F
I
G
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001121347
536
60606
M173
A
L
V
E
L
L
N
M
E
V
E
N
S
A
A
Zebra Danio
Brachydanio rerio
Q803T2
813
93581
S416
I
E
S
F
L
E
S
S
R
S
K
F
I
G
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647806
927
104655
S462
I
D
Q
F
L
D
I
S
R
N
K
F
I
G
Y
Honey Bee
Apis mellifera
XP_395792
817
94676
S408
V
D
T
F
L
E
V
S
R
L
K
F
V
G
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785913
741
84185
L353
D
T
T
T
L
A
G
L
P
H
P
I
H
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
98.5
85.1
N.A.
97.9
97.8
N.A.
70.5
N.A.
54.1
83.5
N.A.
44.7
51.6
N.A.
53.8
Protein Similarity:
100
95.3
98.6
86.2
N.A.
99.1
98.9
N.A.
73
N.A.
57.7
89.7
N.A.
61.5
68.5
N.A.
68.5
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
100
N.A.
6.6
93.3
N.A.
66.6
60
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
100
N.A.
26.6
93.3
N.A.
86.6
80
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
9
0
0
0
0
0
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
17
0
0
0
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
67
0
9
0
67
0
0
9
0
9
0
0
9
0
% E
% Phe:
0
0
0
75
0
0
0
0
0
0
0
75
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
0
0
75
9
% G
% His:
9
0
0
0
0
0
0
0
0
17
0
0
9
0
0
% H
% Ile:
67
0
0
9
0
0
9
0
0
0
0
9
67
0
9
% I
% Lys:
0
0
0
0
9
0
0
9
0
0
84
0
0
0
0
% K
% Leu:
0
9
0
0
92
9
9
9
0
9
0
0
0
0
0
% L
% Met:
0
0
50
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
9
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
75
0
0
0
0
0
0
% R
% Ser:
0
0
17
0
0
0
59
75
0
59
0
0
9
9
0
% S
% Thr:
0
9
17
9
0
9
0
0
0
0
0
0
9
0
0
% T
% Val:
9
0
9
0
0
0
9
0
0
9
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
75
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _