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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM40A
All Species:
25.45
Human Site:
Y489
Identified Species:
50.91
UniProt:
Q5VSL9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VSL9
NP_149079.2
837
95576
Y489
Q
A
Q
M
E
E
E
Y
L
R
S
P
L
S
G
Chimpanzee
Pan troglodytes
XP_524802
813
93885
Y465
Q
A
Q
M
E
E
E
Y
L
R
S
P
L
S
G
Rhesus Macaque
Macaca mulatta
XP_001099183
839
95665
Y491
Q
A
Q
M
E
E
E
Y
L
R
S
P
L
S
G
Dog
Lupus familis
XP_547238
729
83928
Y412
L
L
P
S
L
P
Q
Y
M
I
A
L
L
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8C079
837
95566
Y489
Q
A
Q
M
E
E
E
Y
L
R
S
P
L
S
G
Rat
Rattus norvegicus
XP_001068288
837
95591
Y489
Q
A
Q
M
E
E
E
Y
L
R
S
P
L
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505396
1036
116496
Y478
Q
A
Q
M
E
E
E
Y
L
R
S
P
L
S
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001121347
536
60606
E222
E
A
E
G
D
S
P
E
W
R
A
M
R
E
T
Zebra Danio
Brachydanio rerio
Q803T2
813
93581
F465
Q
I
A
K
E
E
A
F
Q
K
T
P
L
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647806
927
104655
I511
Q
I
K
K
E
E
D
I
A
R
N
P
I
S
T
Honey Bee
Apis mellifera
XP_395792
817
94676
M457
Q
I
Q
K
E
E
Q
M
L
R
N
P
I
S
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785913
741
84185
S402
S
A
S
S
S
V
E
S
L
Y
Q
S
M
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
98.5
85.1
N.A.
97.9
97.8
N.A.
70.5
N.A.
54.1
83.5
N.A.
44.7
51.6
N.A.
53.8
Protein Similarity:
100
95.3
98.6
86.2
N.A.
99.1
98.9
N.A.
73
N.A.
57.7
89.7
N.A.
61.5
68.5
N.A.
68.5
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
100
N.A.
13.3
46.6
N.A.
40
53.3
N.A.
20
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
100
N.A.
40
66.6
N.A.
66.6
73.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
67
9
0
0
0
9
0
9
0
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
9
0
75
75
59
9
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
59
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
25
0
0
0
0
0
9
0
9
0
0
17
0
9
% I
% Lys:
0
0
9
25
0
0
0
0
0
9
0
0
0
9
0
% K
% Leu:
9
9
0
0
9
0
0
0
67
0
0
9
67
9
0
% L
% Met:
0
0
0
50
0
0
0
9
9
0
0
9
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% N
% Pro:
0
0
9
0
0
9
9
0
0
0
0
75
0
0
9
% P
% Gln:
75
0
59
0
0
0
17
0
9
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
75
0
0
9
0
0
% R
% Ser:
9
0
9
17
9
9
0
9
0
0
50
9
0
75
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
25
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _