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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC42BPA All Species: 22.42
Human Site: S1644 Identified Species: 54.81
UniProt: Q5VT25 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VT25 NP_003598.2 1732 197307 S1644 R S S A Q N G S A L K R E F S
Chimpanzee Pan troglodytes XP_510180 1757 198525 A1669 Q E E R P G P A P T N L A R Q
Rhesus Macaque Macaca mulatta XP_001088134 1781 202813 S1693 R S S A Q N G S A L K R E F S
Dog Lupus familis XP_851425 1732 197292 S1644 R S S A Q N G S A L K R E F S
Cat Felis silvestris
Mouse Mus musculus Q3UU96 1719 195518 S1631 R S S A Q N G S A L K R E F S
Rat Rattus norvegicus O54874 1732 197045 S1644 R S S A Q N G S A L K R E F S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513203 1718 195063 S1630 R S S A Q N G S A L R R E L S
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1B0 1637 186706 P1549 R S K M I S A P T N F N H I S
Honey Bee Apis mellifera XP_395596 1741 197744 G1646 S H I S R N S G Y S P H N G S
Nematode Worm Caenorhab. elegans P92199 1173 135756 P1086 K L S D I I R P T P A F E C K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.5 95.6 96.8 N.A. 95.3 95.9 N.A. 88.3 N.A. N.A. N.A. N.A. 44.3 50.4 24.4 N.A.
Protein Similarity: 100 76.3 96.2 99 N.A. 97.8 98.3 N.A. 94.5 N.A. N.A. N.A. N.A. 63.6 67.8 42.3 N.A.
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 86.6 N.A. N.A. N.A. N.A. 20 13.3 13.3 N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. 93.3 N.A. N.A. N.A. N.A. 26.6 26.6 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 60 0 0 10 10 60 0 10 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 10 0 0 0 0 0 0 0 0 0 70 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 10 0 50 0 % F
% Gly: 0 0 0 0 0 10 60 10 0 0 0 0 0 10 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 10 10 0 0 % H
% Ile: 0 0 10 0 20 10 0 0 0 0 0 0 0 10 0 % I
% Lys: 10 0 10 0 0 0 0 0 0 0 50 0 0 0 10 % K
% Leu: 0 10 0 0 0 0 0 0 0 60 0 10 0 10 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 70 0 0 0 10 10 10 10 0 0 % N
% Pro: 0 0 0 0 10 0 10 20 10 10 10 0 0 0 0 % P
% Gln: 10 0 0 0 60 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 70 0 0 10 10 0 10 0 0 0 10 60 0 10 0 % R
% Ser: 10 70 70 10 0 10 10 60 0 10 0 0 0 0 80 % S
% Thr: 0 0 0 0 0 0 0 0 20 10 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _