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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOSC1 All Species: 44.85
Human Site: S226 Identified Species: 89.7
UniProt: Q5VT66 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VT66 NP_073583.3 337 37499 S226 A S L A D L N S R L E K K V K
Chimpanzee Pan troglodytes XP_001172926 337 37497 S226 A S L A D L N S R L E K K V K
Rhesus Macaque Macaca mulatta XP_001102284 337 37383 S226 A S L A D L N S R L E K K V K
Dog Lupus familis XP_545718 412 44485 S301 A S L A D L N S R L E K K V K
Cat Felis silvestris
Mouse Mus musculus Q9CW42 340 37960 S229 A S L E D L N S R L E R R V K
Rat Rattus norvegicus O88994 338 38230 T227 A S L V D L N T R L Q K K V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511827 339 37392 S228 A S L A D L N S R L E K K V K
Chicken Gallus gallus XP_426119 334 37265 T223 A S L K D L N T R L E K K V K
Frog Xenopus laevis Q5U534 343 38202 S230 T S M E A L N S R L E Q P V S
Zebra Danio Brachydanio rerio Q58EJ9 325 36698 S218 A S V G D L N S R L D K D L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120819 341 38547 T217 A S V T D L N T R L E K P V N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781060 330 36744 S215 T S L I N L N S K L D Q Q L H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 96.7 61.8 N.A. 78.2 60 N.A. 67.5 61.7 51.5 45.4 N.A. N.A. 40.1 N.A. 36.5
Protein Similarity: 100 99.4 97.9 68.1 N.A. 85.8 78.1 N.A. 80.2 74.4 68.8 66.7 N.A. N.A. 54.8 N.A. 58.4
P-Site Identity: 100 100 100 100 N.A. 80 80 N.A. 100 86.6 53.3 60 N.A. N.A. 66.6 N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 93.3 66.6 80 N.A. N.A. 80 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 84 0 0 42 9 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 84 0 0 0 0 0 17 0 9 0 0 % D
% Glu: 0 0 0 17 0 0 0 0 0 0 75 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 9 0 0 0 0 9 0 0 75 59 0 67 % K
% Leu: 0 0 75 0 0 100 0 0 0 100 0 0 0 17 0 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 100 0 0 0 0 0 0 0 9 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 17 9 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 92 0 0 9 9 0 0 % R
% Ser: 0 100 0 0 0 0 0 75 0 0 0 0 0 0 17 % S
% Thr: 17 0 0 9 0 0 0 25 0 0 0 0 0 0 0 % T
% Val: 0 0 17 9 0 0 0 0 0 0 0 0 0 84 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _