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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF220 All Species: 22.42
Human Site: S269 Identified Species: 49.33
UniProt: Q5VTB9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VTB9 NP_060620.2 566 62765 S269 M A P G T P K S L L L S A S I
Chimpanzee Pan troglodytes XP_001150146 566 62644 S269 M A P G T P K S L L L S A S I
Rhesus Macaque Macaca mulatta XP_001093291 616 67597 S269 M A P G T P K S L L L S A S I
Dog Lupus familis XP_850815 566 62658 S269 M A P G T P K S L L L S A S I
Cat Felis silvestris
Mouse Mus musculus Q6PDX6 566 62675 S269 M A P G T P K S L L L S A S I
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515673 414 43208 Q141 S L L H L H P Q F A P P N L D
Chicken Gallus gallus NP_001103457 589 65420 S268 M A A G T P K S I L L S A S I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_686354 557 61590 P266 K E C L S A G P P K S L F S M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651088 398 43836 A125 A A P P P A A A T P S V A A A
Honey Bee Apis mellifera XP_001120981 374 41701 N100 Q A R I R V K N R K R K A D E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784311 466 51001 C193 D T M L C P V C F V P L I G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 86.8 99.2 N.A. 97.8 N.A. N.A. 47.3 90.8 N.A. 63.7 N.A. 26.1 30.2 N.A. 26.8
Protein Similarity: 100 96.2 88.4 100 N.A. 99.2 N.A. N.A. 52.8 93.2 N.A. 78.9 N.A. 41.1 41.8 N.A. 42.9
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 0 86.6 N.A. 6.6 N.A. 20 20 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 0 93.3 N.A. 20 N.A. 33.3 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 73 10 0 0 19 10 10 0 10 0 0 73 10 10 % A
% Cys: 0 0 10 0 10 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 19 0 0 0 10 0 0 % F
% Gly: 0 0 0 55 0 0 10 0 0 0 0 0 0 10 0 % G
% His: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 10 0 0 0 10 0 55 % I
% Lys: 10 0 0 0 0 0 64 0 0 19 0 10 0 0 0 % K
% Leu: 0 10 10 19 10 0 0 0 46 55 55 19 0 10 0 % L
% Met: 55 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % N
% Pro: 0 0 55 10 10 64 10 10 10 10 19 10 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 10 0 0 0 10 0 10 0 0 0 0 % R
% Ser: 10 0 0 0 10 0 0 55 0 0 19 55 0 64 10 % S
% Thr: 0 10 0 0 55 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 10 10 0 0 10 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _