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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF220
All Species:
22.73
Human Site:
S273
Identified Species:
50
UniProt:
Q5VTB9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VTB9
NP_060620.2
566
62765
S273
T
P
K
S
L
L
L
S
A
S
I
K
R
E
G
Chimpanzee
Pan troglodytes
XP_001150146
566
62644
S273
T
P
K
S
L
L
L
S
A
S
I
K
R
E
G
Rhesus Macaque
Macaca mulatta
XP_001093291
616
67597
S273
T
P
K
S
L
L
L
S
A
S
I
K
R
E
G
Dog
Lupus familis
XP_850815
566
62658
S273
T
P
K
S
L
L
L
S
A
S
I
K
R
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDX6
566
62675
S273
T
P
K
S
L
L
L
S
A
S
I
K
R
E
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515673
414
43208
P145
L
H
P
Q
F
A
P
P
N
L
D
C
T
P
I
Chicken
Gallus gallus
NP_001103457
589
65420
S272
T
P
K
S
I
L
L
S
A
S
I
K
R
E
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686354
557
61590
L270
S
A
G
P
P
K
S
L
F
S
M
H
I
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651088
398
43836
V129
P
A
A
A
T
P
S
V
A
A
A
E
S
S
Q
Honey Bee
Apis mellifera
XP_001120981
374
41701
K104
R
V
K
N
R
K
R
K
A
D
E
P
S
C
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784311
466
51001
L197
C
P
V
C
F
V
P
L
I
G
S
E
V
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
86.8
99.2
N.A.
97.8
N.A.
N.A.
47.3
90.8
N.A.
63.7
N.A.
26.1
30.2
N.A.
26.8
Protein Similarity:
100
96.2
88.4
100
N.A.
99.2
N.A.
N.A.
52.8
93.2
N.A.
78.9
N.A.
41.1
41.8
N.A.
42.9
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
0
93.3
N.A.
6.6
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
0
100
N.A.
26.6
N.A.
26.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
10
10
0
10
0
0
73
10
10
0
0
0
0
% A
% Cys:
10
0
0
10
0
0
0
0
0
0
0
10
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
10
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
19
0
55
0
% E
% Phe:
0
0
0
0
19
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
55
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
10
0
55
0
10
0
10
% I
% Lys:
0
0
64
0
0
19
0
10
0
0
0
55
0
10
0
% K
% Leu:
10
0
0
0
46
55
55
19
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
10
64
10
10
10
10
19
10
0
0
0
10
0
10
10
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
10
0
0
0
10
0
10
0
0
0
0
0
55
0
19
% R
% Ser:
10
0
0
55
0
0
19
55
0
64
10
0
19
10
0
% S
% Thr:
55
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
10
10
0
0
10
0
10
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _