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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF220 All Species: 22.42
Human Site: T460 Identified Species: 49.33
UniProt: Q5VTB9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VTB9 NP_060620.2 566 62765 T460 A S D E M P S T S N G E S S K
Chimpanzee Pan troglodytes XP_001150146 566 62644 T460 A S D E M P S T S N G E S S K
Rhesus Macaque Macaca mulatta XP_001093291 616 67597 T460 A N D E M P S T S N G E S S K
Dog Lupus familis XP_850815 566 62658 T460 A S D E M P S T S N G E S S K
Cat Felis silvestris
Mouse Mus musculus Q6PDX6 566 62675 T460 A S D E M P S T S N G E G S K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515673 414 43208 G310 G V G V R G L G K L P P G P P
Chicken Gallus gallus NP_001103457 589 65420 T483 A S D E M P S T S N G E S S K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_686354 557 61590 N451 S E T P T T S N G E G D N N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651088 398 43836 P294 S E A T E Q E P A S T S N V E
Honey Bee Apis mellifera XP_001120981 374 41701 V269 I G Q G L V E V K P E P G T T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784311 466 51001 C362 E A C L G V Q C N G E S G M E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 86.8 99.2 N.A. 97.8 N.A. N.A. 47.3 90.8 N.A. 63.7 N.A. 26.1 30.2 N.A. 26.8
Protein Similarity: 100 96.2 88.4 100 N.A. 99.2 N.A. N.A. 52.8 93.2 N.A. 78.9 N.A. 41.1 41.8 N.A. 42.9
P-Site Identity: 100 100 93.3 100 N.A. 93.3 N.A. N.A. 0 100 N.A. 13.3 N.A. 0 0 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. 0 100 N.A. 40 N.A. 33.3 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 55 10 10 0 0 0 0 0 10 0 0 0 0 0 0 % A
% Cys: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 55 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 10 19 0 55 10 0 19 0 0 10 19 55 0 0 19 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 10 10 10 10 0 10 10 10 64 0 37 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 19 0 0 0 0 0 55 % K
% Leu: 0 0 0 10 10 0 10 0 0 10 0 0 0 0 10 % L
% Met: 0 0 0 0 55 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 10 0 0 0 0 0 10 10 55 0 0 19 10 0 % N
% Pro: 0 0 0 10 0 55 0 10 0 10 10 19 0 10 10 % P
% Gln: 0 0 10 0 0 10 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 19 46 0 0 0 0 64 0 55 10 0 19 46 55 0 % S
% Thr: 0 0 10 10 10 10 0 55 0 0 10 0 0 10 10 % T
% Val: 0 10 0 10 0 19 0 10 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _