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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF220
All Species:
25.76
Human Site:
T474
Identified Species:
56.67
UniProt:
Q5VTB9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VTB9
NP_060620.2
566
62765
T474
K
Q
E
A
M
Q
K
T
C
K
N
S
D
I
E
Chimpanzee
Pan troglodytes
XP_001150146
566
62644
T474
K
Q
E
A
M
Q
K
T
C
K
N
S
D
I
E
Rhesus Macaque
Macaca mulatta
XP_001093291
616
67597
T474
K
Q
E
A
M
Q
K
T
C
K
N
S
D
I
E
Dog
Lupus familis
XP_850815
566
62658
T474
K
Q
E
A
M
Q
K
T
C
K
N
S
D
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDX6
566
62675
T474
K
Q
E
A
M
Q
K
T
C
K
N
S
D
I
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515673
414
43208
S324
P
P
P
L
P
G
S
S
G
R
K
G
V
A
R
Chicken
Gallus gallus
NP_001103457
589
65420
T497
K
Q
E
T
M
Q
K
T
C
K
N
S
D
I
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686354
557
61590
T465
L
S
T
T
S
P
R
T
C
K
N
S
E
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651088
398
43836
E308
E
A
P
P
A
S
E
E
P
S
T
S
R
S
T
Honey Bee
Apis mellifera
XP_001120981
374
41701
E283
T
T
P
L
G
Q
S
E
Q
D
E
G
V
S
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784311
466
51001
V376
E
T
E
T
K
H
S
V
K
K
H
V
G
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
86.8
99.2
N.A.
97.8
N.A.
N.A.
47.3
90.8
N.A.
63.7
N.A.
26.1
30.2
N.A.
26.8
Protein Similarity:
100
96.2
88.4
100
N.A.
99.2
N.A.
N.A.
52.8
93.2
N.A.
78.9
N.A.
41.1
41.8
N.A.
42.9
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
0
93.3
N.A.
40
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
13.3
93.3
N.A.
60
N.A.
20
6.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
46
10
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
64
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
55
0
0
% D
% Glu:
19
0
64
0
0
0
10
19
0
0
10
0
10
0
64
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
0
0
10
0
0
19
10
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
55
0
% I
% Lys:
55
0
0
0
10
0
55
0
10
73
10
0
0
0
0
% K
% Leu:
10
0
0
19
0
0
0
0
0
0
0
0
0
19
0
% L
% Met:
0
0
0
0
55
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
64
0
0
0
0
% N
% Pro:
10
10
28
10
10
10
0
0
10
0
0
0
0
0
10
% P
% Gln:
0
55
0
0
0
64
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
10
0
0
10
0
10
% R
% Ser:
0
10
0
0
10
10
28
10
0
10
0
73
0
19
0
% S
% Thr:
10
19
10
28
0
0
0
64
0
0
10
0
0
0
19
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
10
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _