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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANGEL2 All Species: 20.3
Human Site: S233 Identified Species: 37.22
UniProt: Q5VTE6 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VTE6 NP_653168.2 544 62339 S233 Y G A E I R P S L E S L G Y H
Chimpanzee Pan troglodytes XP_001170966 418 47146 C128 T G R K P D G C A I C F K H S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_547407 544 62470 S233 Y G A E I R P S L E S L G Y H
Cat Felis silvestris
Mouse Mus musculus Q8K1C0 544 62394 S233 Y G T E I R P S L E S L G Y H
Rat Rattus norvegicus B2RYM0 667 75323 S308 Y W E Q L E P S L R M M G F T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509976 523 59768 R224 Y H C E F K M R T G R K P D G
Chicken Gallus gallus NP_001026218 558 63638 S245 Y R K E I K S S L E S L G Y H
Frog Xenopus laevis Q6IR85 550 62739 S232 S C D A D I I S L Q E V E T E
Zebra Danio Brachydanio rerio Q5RGT6 569 65312 S265 Y K Q Q I K P S L E S L G Y H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24239 354 40288 C65 E G R D P H K C S S F K V V S
Honey Bee Apis mellifera XP_395873 481 55813 Q192 L F L Y H S D Q L T L I D Y S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797626 569 64453 A249 F Q D F F K P A L E A R G Y A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WKY2 454 52133 K165 D D L D V L L K N R G F R G V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.8 N.A. 93.7 N.A. 85.4 36.1 N.A. 74.2 58.2 20.5 45.6 N.A. 25.3 29.6 N.A. 32.8
Protein Similarity: 100 76.8 N.A. 97 N.A. 91.7 50.2 N.A. 82.3 67.7 34.3 61.3 N.A. 38.5 45.4 N.A. 49.5
P-Site Identity: 100 6.6 N.A. 100 N.A. 93.3 33.3 N.A. 13.3 73.3 13.3 73.3 N.A. 6.6 13.3 N.A. 33.3
P-Site Similarity: 100 20 N.A. 100 N.A. 93.3 60 N.A. 20 80 26.6 86.6 N.A. 13.3 20 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 25 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 8 0 0 0 8 8 0 8 0 0 0 8 % A
% Cys: 0 8 8 0 0 0 0 16 0 0 8 0 0 0 0 % C
% Asp: 8 8 16 16 8 8 8 0 0 0 0 0 8 8 0 % D
% Glu: 8 0 8 39 0 8 0 0 0 47 8 0 8 0 8 % E
% Phe: 8 8 0 8 16 0 0 0 0 0 8 16 0 8 0 % F
% Gly: 0 39 0 0 0 0 8 0 0 8 8 0 54 8 8 % G
% His: 0 8 0 0 8 8 0 0 0 0 0 0 0 8 39 % H
% Ile: 0 0 0 0 39 8 8 0 0 8 0 8 0 0 0 % I
% Lys: 0 8 8 8 0 31 8 8 0 0 0 16 8 0 0 % K
% Leu: 8 0 16 0 8 8 8 0 70 0 8 39 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 8 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 16 0 47 0 0 0 0 0 8 0 0 % P
% Gln: 0 8 8 16 0 0 0 8 0 8 0 0 0 0 0 % Q
% Arg: 0 8 16 0 0 24 0 8 0 16 8 8 8 0 0 % R
% Ser: 8 0 0 0 0 8 8 54 8 8 39 0 0 0 24 % S
% Thr: 8 0 8 0 0 0 0 0 8 8 0 0 0 8 8 % T
% Val: 0 0 0 0 8 0 0 0 0 0 0 8 8 8 8 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 54 0 0 8 0 0 0 0 0 0 0 0 0 54 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _