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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANGEL2 All Species: 18.79
Human Site: S393 Identified Species: 34.44
UniProt: Q5VTE6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VTE6 NP_653168.2 544 62339 S393 S R G Q R I L S I P I W P P N
Chimpanzee Pan troglodytes XP_001170966 418 47146 V285 S Q N C V Y E V Q Q V P K V E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_547407 544 62470 S393 S R G Q R I L S I P I W P P N
Cat Felis silvestris
Mouse Mus musculus Q8K1C0 544 62394 S393 S R G Q R I L S I P I W P P N
Rat Rattus norvegicus B2RYM0 667 75323 K472 S H Q L Y Q R K L Q A P L W P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509976 523 59768 I382 I W P R S L G I S Q N C V Y E
Chicken Gallus gallus NP_001026218 558 63638 S405 P R G Q R I L S I P I W P K K
Frog Xenopus laevis Q6IR85 550 62739 D394 R P G S P T P D P N S I P F V
Zebra Danio Brachydanio rerio Q5RGT6 569 65312 T425 P R G Q R I L T V P I W P R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24239 354 40288 S221 L L F N T K R S D V R C A Q V
Honey Bee Apis mellifera XP_395873 481 55813 T348 H R L H G E G T D K V M L E S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797626 569 64453 S411 R A R V L M R S P L W P K E I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WKY2 454 52133 P321 S G Q T E V E P K E R S F R N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.8 N.A. 93.7 N.A. 85.4 36.1 N.A. 74.2 58.2 20.5 45.6 N.A. 25.3 29.6 N.A. 32.8
Protein Similarity: 100 76.8 N.A. 97 N.A. 91.7 50.2 N.A. 82.3 67.7 34.3 61.3 N.A. 38.5 45.4 N.A. 49.5
P-Site Identity: 100 6.6 N.A. 100 N.A. 100 6.6 N.A. 0 80 13.3 66.6 N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 20 N.A. 100 N.A. 100 13.3 N.A. 13.3 80 13.3 86.6 N.A. 6.6 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 25 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 8 0 8 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 16 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 16 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 8 8 16 0 0 8 0 0 0 16 16 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 8 8 0 % F
% Gly: 0 8 47 0 8 0 16 0 0 0 0 0 0 0 0 % G
% His: 8 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 39 0 8 31 0 39 8 0 0 8 % I
% Lys: 0 0 0 0 0 8 0 8 8 8 0 0 16 8 8 % K
% Leu: 8 8 8 8 8 8 39 0 8 8 0 0 16 0 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 8 8 0 0 0 0 0 8 8 0 0 0 31 % N
% Pro: 16 8 8 0 8 0 8 8 16 39 0 24 47 24 8 % P
% Gln: 0 8 16 39 0 8 0 0 8 24 0 0 0 8 0 % Q
% Arg: 16 47 8 8 39 0 24 0 0 0 16 0 0 16 0 % R
% Ser: 47 0 0 8 8 0 0 47 8 0 8 8 0 0 16 % S
% Thr: 0 0 0 8 8 8 0 16 0 0 0 0 0 0 0 % T
% Val: 0 0 0 8 8 8 0 8 8 8 16 0 8 8 16 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 8 39 0 8 0 % W
% Tyr: 0 0 0 0 8 8 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _