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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANGEL2
All Species:
10
Human Site:
T420
Identified Species:
18.33
UniProt:
Q5VTE6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VTE6
NP_653168.2
544
62339
T420
Q
V
P
K
V
E
K
T
D
S
D
L
T
Q
T
Chimpanzee
Pan troglodytes
XP_001170966
418
47146
A312
Q
T
E
V
L
V
T
A
E
K
L
S
S
N
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547407
544
62470
T420
Q
L
P
K
V
E
K
T
D
S
D
L
T
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1C0
544
62394
T420
Q
V
P
K
V
E
K
T
D
S
D
V
T
Q
A
Rat
Rattus norvegicus
B2RYM0
667
75323
S499
T
S
C
H
P
K
R
S
E
R
L
K
Y
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509976
523
59768
E409
A
V
T
E
A
Q
T
E
E
T
E
I
L
E
A
Chicken
Gallus gallus
NP_001026218
558
63638
A432
Q
Q
Q
K
E
D
D
A
G
E
K
T
E
G
A
Frog
Xenopus laevis
Q6IR85
550
62739
G421
V
V
E
Y
L
T
N
G
G
V
A
D
N
H
K
Zebra Danio
Brachydanio rerio
Q5RGT6
569
65312
D452
T
R
D
S
E
L
R
D
L
E
Q
T
E
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24239
354
40288
G248
D
T
P
I
V
L
T
G
D
F
N
S
L
P
D
Honey Bee
Apis mellifera
XP_395873
481
55813
E375
N
N
S
S
N
Y
C
E
V
N
T
D
T
T
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797626
569
64453
N438
V
M
T
Q
S
S
R
N
S
G
G
A
P
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WKY2
454
52133
Q348
S
L
L
N
E
W
S
Q
E
E
L
Q
L
A
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.8
N.A.
93.7
N.A.
85.4
36.1
N.A.
74.2
58.2
20.5
45.6
N.A.
25.3
29.6
N.A.
32.8
Protein Similarity:
100
76.8
N.A.
97
N.A.
91.7
50.2
N.A.
82.3
67.7
34.3
61.3
N.A.
38.5
45.4
N.A.
49.5
P-Site Identity:
100
6.6
N.A.
93.3
N.A.
86.6
0
N.A.
6.6
13.3
6.6
0
N.A.
20
6.6
N.A.
0
P-Site Similarity:
100
26.6
N.A.
100
N.A.
93.3
26.6
N.A.
53.3
20
13.3
13.3
N.A.
26.6
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
16
0
0
8
8
0
8
24
% A
% Cys:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
8
8
8
31
0
24
16
0
0
8
% D
% Glu:
0
0
16
8
24
24
0
16
31
24
8
0
16
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
16
16
8
8
0
0
16
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
8
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
31
0
8
24
0
0
8
8
8
0
0
8
% K
% Leu:
0
16
8
0
16
16
0
0
8
0
24
16
24
0
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
8
8
0
8
8
0
8
8
0
8
8
8
% N
% Pro:
0
0
31
0
8
0
0
0
0
0
0
0
8
8
0
% P
% Gln:
39
8
8
8
0
8
0
8
0
0
8
8
0
24
0
% Q
% Arg:
0
8
0
0
0
0
24
0
0
8
0
0
0
16
8
% R
% Ser:
8
8
8
16
8
8
8
8
8
24
0
16
8
0
0
% S
% Thr:
16
16
16
0
0
8
24
24
0
8
8
16
31
8
24
% T
% Val:
16
31
0
8
31
8
0
0
8
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _