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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANGEL2
All Species:
11.52
Human Site:
Y137
Identified Species:
21.11
UniProt:
Q5VTE6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VTE6
NP_653168.2
544
62339
Y137
V
I
K
R
N
W
E
Y
I
C
S
H
D
K
E
Chimpanzee
Pan troglodytes
XP_001170966
418
47146
S45
K
F
D
F
S
V
M
S
Y
N
I
L
S
Q
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547407
544
62470
Y137
T
I
Q
R
H
W
E
Y
I
C
N
H
N
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1C0
544
62394
Y137
T
I
K
R
N
W
E
Y
L
C
S
H
N
K
E
Rat
Rattus norvegicus
B2RYM0
667
75323
Y212
P
P
P
M
E
I
P
Y
H
E
I
L
W
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509976
523
59768
V135
I
L
G
R
K
N
K
V
P
R
F
K
E
E
K
Chicken
Gallus gallus
NP_001026218
558
63638
E149
V
N
I
K
R
H
W
E
Y
F
C
Q
H
S
R
Frog
Xenopus laevis
Q6IR85
550
62739
M146
L
Y
Q
E
P
D
G
M
R
K
L
L
N
Y
M
Zebra Danio
Brachydanio rerio
Q5RGT6
569
65312
P169
A
N
R
T
S
A
V
P
E
L
K
R
H
W
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24239
354
40288
Honey Bee
Apis mellifera
XP_395873
481
55813
Y109
S
F
N
I
L
A
Q
Y
L
L
E
T
Y
R
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797626
569
64453
I158
A
S
Q
S
G
T
E
I
K
S
T
Y
R
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WKY2
454
52133
V82
K
E
K
I
S
S
S
V
E
R
E
W
V
F
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.8
N.A.
93.7
N.A.
85.4
36.1
N.A.
74.2
58.2
20.5
45.6
N.A.
25.3
29.6
N.A.
32.8
Protein Similarity:
100
76.8
N.A.
97
N.A.
91.7
50.2
N.A.
82.3
67.7
34.3
61.3
N.A.
38.5
45.4
N.A.
49.5
P-Site Identity:
100
0
N.A.
60
N.A.
80
13.3
N.A.
6.6
6.6
0
6.6
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
20
N.A.
93.3
N.A.
93.3
20
N.A.
46.6
13.3
20
20
N.A.
0
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
24
8
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
0
0
0
0
0
8
0
16
% D
% Glu:
0
8
0
8
8
0
31
8
16
8
16
0
8
8
31
% E
% Phe:
0
16
0
8
0
0
0
0
0
8
8
0
0
8
8
% F
% Gly:
0
0
8
0
8
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
8
0
0
8
0
0
24
16
0
0
% H
% Ile:
8
24
8
16
0
8
0
8
16
0
16
0
0
0
0
% I
% Lys:
16
0
24
8
8
0
8
0
8
8
8
8
0
31
8
% K
% Leu:
8
8
0
0
8
0
0
0
16
16
8
24
0
0
0
% L
% Met:
0
0
0
8
0
0
8
8
0
0
0
0
0
0
8
% M
% Asn:
0
16
8
0
16
8
0
0
0
8
8
0
24
0
0
% N
% Pro:
8
8
8
0
8
0
8
8
8
0
0
0
0
0
0
% P
% Gln:
0
0
24
0
0
0
8
0
0
0
0
8
0
8
0
% Q
% Arg:
0
0
8
31
8
0
0
0
8
16
0
8
8
16
16
% R
% Ser:
8
8
0
8
24
8
8
8
0
8
16
0
8
8
8
% S
% Thr:
16
0
0
8
0
8
0
0
0
0
8
8
0
0
0
% T
% Val:
16
0
0
0
0
8
8
16
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
24
8
0
0
0
0
8
8
8
0
% W
% Tyr:
0
8
0
0
0
0
0
39
16
0
0
8
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _