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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANGEL2 All Species: 8.18
Human Site: Y21 Identified Species: 15
UniProt: Q5VTE6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VTE6 NP_653168.2 544 62339 Y21 C V V G R G R Y P M F P H H S
Chimpanzee Pan troglodytes XP_001170966 418 47146
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_547407 544 62470 Y21 C V V G R G R Y P M L P H H Q
Cat Felis silvestris
Mouse Mus musculus Q8K1C0 544 62394 Y21 C V A G R G R Y S M F P Y P L
Rat Rattus norvegicus B2RYM0 667 75323 D96 S S L A L L M D N S G E Q D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509976 523 59768 S19 D W I T L W E S P W R F C W N
Chicken Gallus gallus NP_001026218 558 63638 M33 S S P V P T C M R W A G H C P
Frog Xenopus laevis Q6IR85 550 62739 H30 V A N G K K S H W D E L E I S
Zebra Danio Brachydanio rerio Q5RGT6 569 65312 G53 W R H W Y Q P G H L W W T Q P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24239 354 40288
Honey Bee Apis mellifera XP_395873 481 55813
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797626 569 64453 L42 R E S K K H D L R T S S S Q G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WKY2 454 52133
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.8 N.A. 93.7 N.A. 85.4 36.1 N.A. 74.2 58.2 20.5 45.6 N.A. 25.3 29.6 N.A. 32.8
Protein Similarity: 100 76.8 N.A. 97 N.A. 91.7 50.2 N.A. 82.3 67.7 34.3 61.3 N.A. 38.5 45.4 N.A. 49.5
P-Site Identity: 100 0 N.A. 86.6 N.A. 66.6 0 N.A. 6.6 6.6 13.3 0 N.A. 0 0 N.A. 0
P-Site Similarity: 100 0 N.A. 86.6 N.A. 73.3 13.3 N.A. 20 6.6 26.6 13.3 N.A. 0 0 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 25 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 8 0 0 0 0 0 0 8 0 0 0 0 % A
% Cys: 24 0 0 0 0 0 8 0 0 0 0 0 8 8 0 % C
% Asp: 8 0 0 0 0 0 8 8 0 8 0 0 0 8 0 % D
% Glu: 0 8 0 0 0 0 8 0 0 0 8 8 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 16 8 0 0 0 % F
% Gly: 0 0 0 31 0 24 0 8 0 0 8 8 0 0 8 % G
% His: 0 0 8 0 0 8 0 8 8 0 0 0 24 16 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 8 16 8 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 0 16 8 0 8 0 8 8 8 0 0 8 % L
% Met: 0 0 0 0 0 0 8 8 0 24 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 8 % N
% Pro: 0 0 8 0 8 0 8 0 24 0 0 24 0 8 16 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 0 0 8 16 8 % Q
% Arg: 8 8 0 0 24 0 24 0 16 0 8 0 0 0 0 % R
% Ser: 16 16 8 0 0 0 8 8 8 8 8 8 8 0 16 % S
% Thr: 0 0 0 8 0 8 0 0 0 8 0 0 8 0 8 % T
% Val: 8 24 16 8 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 8 8 0 8 0 8 0 0 8 16 8 8 0 8 0 % W
% Tyr: 0 0 0 0 8 0 0 24 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _