KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANGEL2
All Species:
23.33
Human Site:
Y226
Identified Species:
42.78
UniProt:
Q5VTE6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VTE6
NP_653168.2
544
62339
Y226
Q
E
V
Q
E
D
H
Y
G
A
E
I
R
P
S
Chimpanzee
Pan troglodytes
XP_001170966
418
47146
T121
H
C
E
Y
K
M
R
T
G
R
K
P
D
G
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547407
544
62470
Y226
Q
E
V
Q
E
D
H
Y
G
A
E
I
R
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1C0
544
62394
Y226
Q
E
V
Q
E
D
H
Y
G
T
E
I
R
P
S
Rat
Rattus norvegicus
B2RYM0
667
75323
Y301
Q
E
V
Q
E
D
H
Y
W
E
Q
L
E
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509976
523
59768
Y217
P
S
L
E
S
L
G
Y
H
C
E
F
K
M
R
Chicken
Gallus gallus
NP_001026218
558
63638
Y238
Q
E
V
Q
E
D
H
Y
R
K
E
I
K
S
S
Frog
Xenopus laevis
Q6IR85
550
62739
S225
G
I
M
D
E
I
I
S
C
D
A
D
I
I
S
Zebra Danio
Brachydanio rerio
Q5RGT6
569
65312
Y258
Q
E
V
Q
E
D
H
Y
K
Q
Q
I
K
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24239
354
40288
E58
T
S
L
G
N
Q
A
E
G
R
D
P
H
K
C
Honey Bee
Apis mellifera
XP_395873
481
55813
L185
N
D
K
K
D
G
L
L
F
L
Y
H
S
D
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797626
569
64453
F242
Q
E
V
E
S
R
H
F
Q
D
F
F
K
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WKY2
454
52133
D158
L
Q
E
V
D
R
F
D
D
L
D
V
L
L
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.8
N.A.
93.7
N.A.
85.4
36.1
N.A.
74.2
58.2
20.5
45.6
N.A.
25.3
29.6
N.A.
32.8
Protein Similarity:
100
76.8
N.A.
97
N.A.
91.7
50.2
N.A.
82.3
67.7
34.3
61.3
N.A.
38.5
45.4
N.A.
49.5
P-Site Identity:
100
6.6
N.A.
100
N.A.
93.3
66.6
N.A.
13.3
73.3
13.3
73.3
N.A.
6.6
0
N.A.
33.3
P-Site Similarity:
100
20
N.A.
100
N.A.
93.3
80
N.A.
33.3
80
20
86.6
N.A.
20
20
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
25
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
16
8
0
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
8
8
0
0
0
0
16
% C
% Asp:
0
8
0
8
16
47
0
8
8
16
16
8
8
8
0
% D
% Glu:
0
54
16
16
54
0
0
8
0
8
39
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
8
8
8
0
8
16
0
0
0
% F
% Gly:
8
0
0
8
0
8
8
0
39
0
0
0
0
8
0
% G
% His:
8
0
0
0
0
0
54
0
8
0
0
8
8
0
0
% H
% Ile:
0
8
0
0
0
8
8
0
0
0
0
39
8
8
0
% I
% Lys:
0
0
8
8
8
0
0
0
8
8
8
0
31
8
8
% K
% Leu:
8
0
16
0
0
8
8
8
0
16
0
8
8
8
0
% L
% Met:
0
0
8
0
0
8
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
16
0
47
0
% P
% Gln:
54
8
0
47
0
8
0
0
8
8
16
0
0
0
8
% Q
% Arg:
0
0
0
0
0
16
8
0
8
16
0
0
24
0
8
% R
% Ser:
0
16
0
0
16
0
0
8
0
0
0
0
8
8
54
% S
% Thr:
8
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% T
% Val:
0
0
54
8
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
54
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _