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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANGEL2
All Species:
9.39
Human Site:
Y480
Identified Species:
17.22
UniProt:
Q5VTE6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VTE6
NP_653168.2
544
62339
Y480
R
S
A
I
T
V
D
Y
I
F
Y
S
A
E
K
Chimpanzee
Pan troglodytes
XP_001170966
418
47146
V372
A
G
H
P
G
A
E
V
A
L
V
G
G
L
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547407
544
62470
Y480
R
S
A
I
T
V
D
Y
I
F
Y
S
A
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1C0
544
62394
Y480
R
S
A
I
T
V
D
Y
I
F
Y
T
A
K
K
Rat
Rattus norvegicus
B2RYM0
667
75323
P559
S
E
L
E
P
V
F
P
R
T
I
G
T
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509976
523
59768
E469
Y
S
A
A
K
E
E
E
P
M
Q
P
G
A
E
Chicken
Gallus gallus
NP_001026218
558
63638
D492
S
R
S
A
V
T
V
D
Y
I
F
Y
S
A
A
Frog
Xenopus laevis
Q6IR85
550
62739
G481
N
Y
T
F
D
F
K
G
V
I
D
Y
I
F
Y
Zebra Danio
Brachydanio rerio
Q5RGT6
569
65312
M512
S
A
A
L
G
D
V
M
A
Q
A
E
Y
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24239
354
40288
G308
D
Y
I
L
R
S
L
G
S
R
S
R
H
K
L
Honey Bee
Apis mellifera
XP_395873
481
55813
I435
E
W
I
T
V
D
Y
I
F
Y
S
G
L
E
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797626
569
64453
V498
H
S
S
T
N
C
T
V
D
Y
I
F
Y
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WKY2
454
52133
T408
T
V
D
Y
I
W
H
T
K
E
L
V
P
V
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.8
N.A.
93.7
N.A.
85.4
36.1
N.A.
74.2
58.2
20.5
45.6
N.A.
25.3
29.6
N.A.
32.8
Protein Similarity:
100
76.8
N.A.
97
N.A.
91.7
50.2
N.A.
82.3
67.7
34.3
61.3
N.A.
38.5
45.4
N.A.
49.5
P-Site Identity:
100
6.6
N.A.
100
N.A.
86.6
6.6
N.A.
13.3
0
0
6.6
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
13.3
N.A.
26.6
20
6.6
20
N.A.
13.3
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
39
16
0
8
0
0
16
0
8
0
24
16
16
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
8
16
24
8
8
0
8
0
0
0
0
% D
% Glu:
8
8
0
8
0
8
16
8
0
8
0
8
0
24
16
% E
% Phe:
0
0
0
8
0
8
8
0
8
24
8
8
0
8
0
% F
% Gly:
0
8
0
0
16
0
0
16
0
0
0
24
16
0
0
% G
% His:
8
0
8
0
0
0
8
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
16
24
8
0
0
8
24
16
16
0
8
8
0
% I
% Lys:
0
0
0
0
8
0
8
0
8
0
0
0
0
16
31
% K
% Leu:
0
0
8
16
0
0
8
0
0
8
8
0
8
8
16
% L
% Met:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
8
0
0
8
8
0
0
8
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
8
% Q
% Arg:
24
8
0
0
8
0
0
0
8
8
0
8
0
0
8
% R
% Ser:
24
39
16
0
0
8
0
0
8
0
16
16
8
16
0
% S
% Thr:
8
0
8
16
24
8
8
8
0
8
0
8
8
0
0
% T
% Val:
0
8
0
0
16
31
16
16
8
0
8
8
0
8
0
% V
% Trp:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
16
0
8
0
0
8
24
8
16
24
16
16
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _