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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLHDC7A All Species: 4.55
Human Site: S325 Identified Species: 11.11
UniProt: Q5VTJ3 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VTJ3 NP_689588.2 777 84479 S325 S P R P P P G S L G T G A A S
Chimpanzee Pan troglodytes XP_524579 777 84267 S325 S P R P P P G S L G T G A A S
Rhesus Macaque Macaca mulatta XP_001116368 545 57734 V128 R L P L K T A V E E A R R G A
Dog Lupus familis XP_544534 1033 110011 P570 P P V P L P G P S G T G A V S
Cat Felis silvestris
Mouse Mus musculus A2APT9 773 83572 V322 G P G P E P L V T G A A S R D
Rat Rattus norvegicus XP_001055129 601 65742 K183 D I L T E K Q K E T Q K L M V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515274 806 86681 L325 N V S V T Q A L G S G A A E P
Chicken Gallus gallus XP_425728 731 80634 A296 H S Q E T T V A L Q D P T T S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001340052 753 84688 V302 T V R Y S R H V V I R Q D S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUU5 623 68905 E206 H N F Q E V M E S E E F L L L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97 30.6 50.2 N.A. 69.2 28.9 N.A. 48 40.9 N.A. 35.7 N.A. 20.2 N.A. N.A. N.A.
Protein Similarity: 100 97.9 41.8 58.4 N.A. 77.2 41.3 N.A. 59.7 54.5 N.A. 52.3 N.A. 32.5 N.A. N.A. N.A.
P-Site Identity: 100 100 0 60 N.A. 26.6 0 N.A. 6.6 13.3 N.A. 6.6 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 6.6 60 N.A. 33.3 0 N.A. 13.3 26.6 N.A. 26.6 N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 20 10 0 0 20 20 40 20 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 10 0 10 0 10 % D
% Glu: 0 0 0 10 30 0 0 10 20 20 10 0 0 10 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 10 0 10 0 0 0 30 0 10 40 10 30 0 10 0 % G
% His: 20 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 10 0 10 0 0 0 10 0 0 0 % K
% Leu: 0 10 10 10 10 0 10 10 30 0 0 0 20 10 10 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % M
% Asn: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 40 10 40 20 40 0 10 0 0 0 10 0 0 10 % P
% Gln: 0 0 10 10 0 10 10 0 0 10 10 10 0 0 0 % Q
% Arg: 10 0 30 0 0 10 0 0 0 0 10 10 10 10 0 % R
% Ser: 20 10 10 0 10 0 0 20 20 10 0 0 10 10 40 % S
% Thr: 10 0 0 10 20 20 0 0 10 10 30 0 10 10 0 % T
% Val: 0 20 10 10 0 10 10 30 10 0 0 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _