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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHDC7A
All Species:
21.82
Human Site:
Y455
Identified Species:
53.33
UniProt:
Q5VTJ3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VTJ3
NP_689588.2
777
84479
Y455
E
A
L
K
E
A
A
Y
K
V
M
S
E
N
Y
Chimpanzee
Pan troglodytes
XP_524579
777
84267
Y455
E
A
L
K
E
A
A
Y
K
V
M
S
E
N
Y
Rhesus Macaque
Macaca mulatta
XP_001116368
545
57734
A237
P
R
D
D
S
P
A
A
D
L
G
R
T
R
P
Dog
Lupus familis
XP_544534
1033
110011
Y711
E
A
L
K
E
A
A
Y
K
V
M
S
D
N
Y
Cat
Felis silvestris
Mouse
Mus musculus
A2APT9
773
83572
Y451
E
T
L
K
E
A
A
Y
K
V
L
S
D
N
Y
Rat
Rattus norvegicus
XP_001055129
601
65742
L293
G
Q
T
V
L
G
V
L
V
L
P
S
L
Y
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515274
806
86681
Y485
D
G
L
K
E
A
A
Y
R
V
M
S
D
N
Y
Chicken
Gallus gallus
XP_425728
731
80634
Y407
D
F
L
Q
E
A
A
Y
K
V
M
S
D
N
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001340052
753
84688
L413
T
A
L
Q
Q
A
A
L
R
V
M
S
D
N
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
R315
Q
G
P
R
T
R
P
R
K
P
T
R
R
G
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
30.6
50.2
N.A.
69.2
28.9
N.A.
48
40.9
N.A.
35.7
N.A.
20.2
N.A.
N.A.
N.A.
Protein Similarity:
100
97.9
41.8
58.4
N.A.
77.2
41.3
N.A.
59.7
54.5
N.A.
52.3
N.A.
32.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
93.3
N.A.
80
6.6
N.A.
73.3
73.3
N.A.
60
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
13.3
N.A.
93.3
93.3
N.A.
86.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
40
0
0
0
70
80
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
10
10
0
0
0
0
10
0
0
0
50
0
0
% D
% Glu:
40
0
0
0
60
0
0
0
0
0
0
0
20
0
10
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
20
0
0
0
10
0
0
0
0
10
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
50
0
0
0
0
60
0
0
0
0
0
0
% K
% Leu:
0
0
70
0
10
0
0
20
0
20
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
60
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
0
% N
% Pro:
10
0
10
0
0
10
10
0
0
10
10
0
0
0
10
% P
% Gln:
10
10
0
20
10
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
10
0
10
0
10
0
10
20
0
0
20
10
10
0
% R
% Ser:
0
0
0
0
10
0
0
0
0
0
0
80
0
0
0
% S
% Thr:
10
10
10
0
10
0
0
0
0
0
10
0
10
0
0
% T
% Val:
0
0
0
10
0
0
10
0
10
70
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
10
70
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _