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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCAF12L1 All Species: 10.3
Human Site: T96 Identified Species: 25.19
UniProt: Q5VU92 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VU92 NP_848565.2 463 51201 T96 E R Q L E L G T V N K V F A S
Chimpanzee Pan troglodytes XP_529143 510 55813 R139 R F A P A L L R Q A A H L W P
Rhesus Macaque Macaca mulatta XP_001089560 463 50773 T96 E R Q L D L G T L N K V F A S
Dog Lupus familis XP_549235 578 63266 T211 E R E L A L G T L N K V F A S
Cat Felis silvestris
Mouse Mus musculus Q8BGW4 469 51604 P102 E R Q L T L G P L N K V F A S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5F3R7 427 47600 K80 R Q V V C G T K C N T L F V V
Frog Xenopus laevis Q63ZP7 446 49593 N83 E R E F H L G N L N K V F A S
Zebra Danio Brachydanio rerio Q08BB3 482 53852 R93 E R E F S L G R L N K V F A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396383 459 52162 N113 E Y S V S L N N M N K V F C S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791553 435 48529 S89 I F A S E W I S D H Q V V L G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.1 87.2 63.4 N.A. 74.1 N.A. N.A. N.A. 57.2 54.4 53.5 N.A. N.A. 38 N.A. 39.3
Protein Similarity: 100 69 92.8 70.9 N.A. 83.5 N.A. N.A. N.A. 70.1 70.6 66.5 N.A. N.A. 57.2 N.A. 57.8
P-Site Identity: 100 6.6 86.6 80 N.A. 80 N.A. N.A. N.A. 13.3 66.6 66.6 N.A. N.A. 46.6 N.A. 13.3
P-Site Similarity: 100 6.6 100 93.3 N.A. 86.6 N.A. N.A. N.A. 33.3 80 80 N.A. N.A. 60 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 0 20 0 0 0 0 10 10 0 0 60 0 % A
% Cys: 0 0 0 0 10 0 0 0 10 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 70 0 30 0 20 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 20 0 20 0 0 0 0 0 0 0 0 80 0 0 % F
% Gly: 0 0 0 0 0 10 60 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 10 0 0 0 0 10 0 10 0 0 0 % H
% Ile: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 70 0 0 0 0 % K
% Leu: 0 0 0 40 0 80 10 0 50 0 0 10 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 20 0 80 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 10 % P
% Gln: 0 10 30 0 0 0 0 0 10 0 10 0 0 0 0 % Q
% Arg: 20 60 0 0 0 0 0 20 0 0 0 0 0 0 0 % R
% Ser: 0 0 10 10 20 0 0 10 0 0 0 0 0 0 70 % S
% Thr: 0 0 0 0 10 0 10 30 0 0 10 0 0 0 0 % T
% Val: 0 0 10 20 0 0 0 0 10 0 0 80 10 10 10 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _