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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CACHD1 All Species: 24.55
Human Site: T268 Identified Species: 60
UniProt: Q5VU97 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VU97 NP_065976.2 1274 142290 T268 H D K I S V L T V A D T V R T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001089910 1478 163450 T472 H D K I S V L T V A D T V R T
Dog Lupus familis XP_536680 1227 137145 V254 K R K M S T F V S S V K S L D
Cat Felis silvestris
Mouse Mus musculus Q6PDJ1 1288 143794 T282 H D K I S V L T V A D A V R T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517545 1393 154321 T393 H D K I S V L T V A D T V R T
Chicken Gallus gallus XP_422524 1294 144253 T285 H D K I S V L T V A D T V R T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001334829 1352 150988 T343 H D K I S V L T I A D T V R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q5BI42 1449 162073 S363 V S L V T V A S E A N F M S L
Honey Bee Apis mellifera XP_396395 1073 120935 L128 Y N I I Q P I L A K N E N L F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798218 1395 154586 N325 I S E N R R L N N R V A I M T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 85.2 94.5 N.A. 96.1 N.A. N.A. 85.4 90.7 N.A. 81.2 N.A. 27.3 28.9 N.A. 39.2
Protein Similarity: 100 N.A. 85.5 95.2 N.A. 97.5 N.A. N.A. 88 94 N.A. 88 N.A. 45 46.3 N.A. 56.4
P-Site Identity: 100 N.A. 100 13.3 N.A. 93.3 N.A. N.A. 100 100 N.A. 86.6 N.A. 13.3 6.6 N.A. 13.3
P-Site Similarity: 100 N.A. 100 26.6 N.A. 93.3 N.A. N.A. 100 100 N.A. 100 N.A. 46.6 33.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 10 70 0 20 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 60 0 0 0 0 0 0 0 0 60 0 0 0 10 % D
% Glu: 0 0 10 0 0 0 0 0 10 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 10 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 10 70 0 0 10 0 10 0 0 0 10 0 0 % I
% Lys: 10 0 70 0 0 0 0 0 0 10 0 10 0 0 0 % K
% Leu: 0 0 10 0 0 0 70 10 0 0 0 0 0 20 10 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 10 10 0 % M
% Asn: 0 10 0 10 0 0 0 10 10 0 20 0 10 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 0 10 10 0 0 0 10 0 0 0 60 0 % R
% Ser: 0 20 0 0 70 0 0 10 10 10 0 0 10 10 10 % S
% Thr: 0 0 0 0 10 10 0 60 0 0 0 50 0 0 60 % T
% Val: 10 0 0 10 0 70 0 10 50 0 20 0 60 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _