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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CACHD1 All Species: 25.76
Human Site: Y1248 Identified Species: 62.96
UniProt: Q5VU97 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VU97 NP_065976.2 1274 142290 Y1248 L S H K F H H Y R S H H P T L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001089910 1478 163450 Y1452 L S H K F H H Y R S H H P T L
Dog Lupus familis XP_536680 1227 137145 Y1201 L S H K F H H Y R P H H P T L
Cat Felis silvestris
Mouse Mus musculus Q6PDJ1 1288 143794 Y1262 L S H K F H H Y R P H H P T L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517545 1393 154321 Y1367 L S H K F H H Y R L H P P S L
Chicken Gallus gallus XP_422524 1294 144253 Y1268 L S H K F H H Y R L H H P T L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001334829 1352 150988 Y1323 L S H K F H P Y R H P H M H H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q5BI42 1449 162073 Y1397 P T S K T E R Y K Q V Q A T P
Honey Bee Apis mellifera XP_396395 1073 120935 S1048 R Q S I C L P S P I T H L G S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798218 1395 154586 T1369 G G I A A R E T L L I L R L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 85.2 94.5 N.A. 96.1 N.A. N.A. 85.4 90.7 N.A. 81.2 N.A. 27.3 28.9 N.A. 39.2
Protein Similarity: 100 N.A. 85.5 95.2 N.A. 97.5 N.A. N.A. 88 94 N.A. 88 N.A. 45 46.3 N.A. 56.4
P-Site Identity: 100 N.A. 100 93.3 N.A. 93.3 N.A. N.A. 80 93.3 N.A. 60 N.A. 20 6.6 N.A. 0
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 N.A. N.A. 86.6 93.3 N.A. 60 N.A. 33.3 6.6 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 0 0 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 70 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % G
% His: 0 0 70 0 0 70 60 0 0 10 60 70 0 10 10 % H
% Ile: 0 0 10 10 0 0 0 0 0 10 10 0 0 0 0 % I
% Lys: 0 0 0 80 0 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 70 0 0 0 0 10 0 0 10 30 0 10 10 10 60 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 0 20 0 10 20 10 10 60 0 10 % P
% Gln: 0 10 0 0 0 0 0 0 0 10 0 10 0 0 0 % Q
% Arg: 10 0 0 0 0 10 10 0 70 0 0 0 10 0 0 % R
% Ser: 0 70 20 0 0 0 0 10 0 20 0 0 0 10 10 % S
% Thr: 0 10 0 0 10 0 0 10 0 0 10 0 0 60 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 80 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _