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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM69B
All Species:
9.39
Human Site:
S129
Identified Species:
22.96
UniProt:
Q5VUD6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VUD6
NP_689634.2
431
48583
S129
T
L
D
S
K
A
R
S
D
A
A
P
R
R
E
Chimpanzee
Pan troglodytes
XP_520376
551
60658
S249
T
L
D
S
K
A
R
S
D
A
A
P
R
R
E
Rhesus Macaque
Macaca mulatta
XP_001094140
422
47003
L120
W
T
P
V
A
K
G
L
P
A
S
L
N
K
Q
Dog
Lupus familis
XP_548369
430
48435
S129
G
L
D
P
K
A
R
S
D
P
A
P
R
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99ML4
431
48773
P129
A
L
N
S
K
A
W
P
D
A
A
P
R
R
E
Rat
Rattus norvegicus
Q5FVL3
431
48819
P129
A
L
N
S
K
A
W
P
D
A
V
P
R
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512336
417
47364
P115
A
F
K
A
E
N
N
P
D
S
T
P
R
R
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DCL6
410
46973
V109
T
L
H
L
D
F
G
V
D
L
E
P
R
K
E
Zebra Danio
Brachydanio rerio
Q1RLQ5
428
48574
E126
V
L
H
Y
E
L
G
E
E
L
E
P
K
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192983
336
38418
S103
I
N
N
D
G
K
V
S
L
A
E
A
K
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.3
81.9
88.6
N.A.
88.8
88.4
N.A.
67.5
N.A.
47
45.4
N.A.
N.A.
N.A.
N.A.
29.7
Protein Similarity:
100
77.6
86.3
93
N.A.
92.3
92.1
N.A.
80
N.A.
65.1
63.8
N.A.
N.A.
N.A.
N.A.
47.1
P-Site Identity:
100
100
6.6
73.3
N.A.
73.3
66.6
N.A.
33.3
N.A.
40
20
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
26.6
80
N.A.
80
73.3
N.A.
53.3
N.A.
46.6
46.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
0
10
10
50
0
0
0
60
40
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
30
10
10
0
0
0
70
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
20
0
0
10
10
0
30
0
0
0
80
% E
% Phe:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
0
30
0
0
0
0
0
0
0
0
% G
% His:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
50
20
0
0
0
0
0
0
20
30
0
% K
% Leu:
0
70
0
10
0
10
0
10
10
20
0
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
30
0
0
10
10
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
10
10
0
0
0
30
10
10
0
80
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% Q
% Arg:
0
0
0
0
0
0
30
0
0
0
0
0
70
50
0
% R
% Ser:
0
0
0
40
0
0
0
40
0
10
10
0
0
0
0
% S
% Thr:
30
10
0
0
0
0
0
0
0
0
10
0
0
10
0
% T
% Val:
10
0
0
10
0
0
10
10
0
0
10
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _