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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM69B
All Species:
19.39
Human Site:
T114
Identified Species:
47.41
UniProt:
Q5VUD6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VUD6
NP_689634.2
431
48583
T114
L
W
R
D
K
D
V
T
I
K
C
G
I
E
E
Chimpanzee
Pan troglodytes
XP_520376
551
60658
T234
L
W
R
D
K
D
V
T
I
K
C
G
I
E
E
Rhesus Macaque
Macaca mulatta
XP_001094140
422
47003
R105
G
V
W
G
S
R
R
R
G
L
V
W
G
L
E
Dog
Lupus familis
XP_548369
430
48435
T114
L
W
Q
G
K
E
V
T
I
K
C
G
I
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99ML4
431
48773
T114
L
W
Q
D
K
E
V
T
I
K
C
G
I
E
E
Rat
Rattus norvegicus
Q5FVL3
431
48819
T114
L
W
Q
D
K
E
V
T
I
K
C
G
I
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512336
417
47364
I100
L
W
K
G
R
A
V
I
I
K
C
G
I
Q
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DCL6
410
46973
V94
I
W
G
N
L
E
G
V
I
K
C
Q
M
E
N
Zebra Danio
Brachydanio rerio
Q1RLQ5
428
48574
V111
S
W
G
D
Q
D
G
V
I
K
C
Q
L
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192983
336
38418
T88
S
Y
F
V
K
F
Q
T
K
I
F
D
I
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.3
81.9
88.6
N.A.
88.8
88.4
N.A.
67.5
N.A.
47
45.4
N.A.
N.A.
N.A.
N.A.
29.7
Protein Similarity:
100
77.6
86.3
93
N.A.
92.3
92.1
N.A.
80
N.A.
65.1
63.8
N.A.
N.A.
N.A.
N.A.
47.1
P-Site Identity:
100
100
6.6
80
N.A.
86.6
86.6
N.A.
60
N.A.
33.3
40
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
6.6
93.3
N.A.
100
100
N.A.
80
N.A.
60
60
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
80
0
0
0
0
% C
% Asp:
0
0
0
50
0
30
0
0
0
0
0
10
0
0
20
% D
% Glu:
0
0
0
0
0
40
0
0
0
0
0
0
0
60
70
% E
% Phe:
0
0
10
0
0
10
0
0
0
0
10
0
0
0
0
% F
% Gly:
10
0
20
30
0
0
20
0
10
0
0
60
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
10
80
10
0
0
70
0
0
% I
% Lys:
0
0
10
0
60
0
0
0
10
80
0
0
0
0
0
% K
% Leu:
60
0
0
0
10
0
0
0
0
10
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
30
0
10
0
10
0
0
0
0
20
0
10
0
% Q
% Arg:
0
0
20
0
10
10
10
10
0
0
0
0
0
0
0
% R
% Ser:
20
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
60
0
0
0
0
0
0
0
% T
% Val:
0
10
0
10
0
0
60
20
0
0
10
0
0
0
0
% V
% Trp:
0
80
10
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _