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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFMBT2 All Species: 22.12
Human Site: T500 Identified Species: 48.67
UniProt: Q5VUG0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VUG0 NP_001025051.1 894 100563 T500 P E K Q L P P T V P V K K I P
Chimpanzee Pan troglodytes XP_001172770 866 98137 S476 P E K Q V P S S R T V H E G L
Rhesus Macaque Macaca mulatta XP_001118715 881 99406 T487 P E K Q L P P T V P V K K I P
Dog Lupus familis XP_850333 894 100542 T500 P E K Q L P S T V P V E K I P
Cat Felis silvestris
Mouse Mus musculus Q5DTW2 938 105962 P498 M E K Q L L S P V P I E K I P
Rat Rattus norvegicus Q9JMD2 863 97487 S474 P E K Q I L S S R T V H E G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516002 1244 137829 T851 P E K Q L P S T V P V E K I P
Chicken Gallus gallus XP_414254 867 97536 S477 P E K Q I L S S R S V H D G L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_683042 858 97357 F469 L W K S H T I F I L F P L H H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120398 860 97859 S490 K D G G S P N S L N S K Q H S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202275 1967 214741 M1357 E K Q R F A P M S P G R D L Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.9 94.7 92 N.A. 72.2 53.4 N.A. 63.7 54.7 N.A. 60.7 N.A. N.A. 21 N.A. 21.5
Protein Similarity: 100 69.2 95.9 94.7 N.A. 82.9 68.6 N.A. 67 69.8 N.A. 74 N.A. N.A. 39.8 N.A. 31.8
P-Site Identity: 100 40 100 86.6 N.A. 60 33.3 N.A. 86.6 33.3 N.A. 6.6 N.A. N.A. 13.3 N.A. 13.3
P-Site Similarity: 100 60 100 93.3 N.A. 73.3 53.3 N.A. 93.3 46.6 N.A. 13.3 N.A. N.A. 40 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 0 0 19 0 0 % D
% Glu: 10 73 0 0 0 0 0 0 0 0 0 28 19 0 0 % E
% Phe: 0 0 0 0 10 0 0 10 0 0 10 0 0 0 0 % F
% Gly: 0 0 10 10 0 0 0 0 0 0 10 0 0 28 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 28 0 19 10 % H
% Ile: 0 0 0 0 19 0 10 0 10 0 10 0 0 46 0 % I
% Lys: 10 10 82 0 0 0 0 0 0 0 0 28 46 0 0 % K
% Leu: 10 0 0 0 46 28 0 0 10 10 0 0 10 10 28 % L
% Met: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % N
% Pro: 64 0 0 0 0 55 28 10 0 55 0 10 0 0 46 % P
% Gln: 0 0 10 73 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 10 0 0 0 0 28 0 0 10 0 0 0 % R
% Ser: 0 0 0 10 10 0 55 37 10 10 10 0 0 0 10 % S
% Thr: 0 0 0 0 0 10 0 37 0 19 0 0 0 0 0 % T
% Val: 0 0 0 0 10 0 0 0 46 0 64 0 0 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _