KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AADACL4
All Species:
14.55
Human Site:
S78
Identified Species:
35.56
UniProt:
Q5VUY2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VUY2
NP_001013652.1
407
46082
S78
F
I
R
F
L
H
D
S
V
R
I
K
K
D
P
Chimpanzee
Pan troglodytes
XP_525200
407
46031
S78
F
I
R
F
L
H
D
S
V
R
I
K
K
D
P
Rhesus Macaque
Macaca mulatta
XP_001106030
407
46143
S78
F
I
R
F
L
H
D
S
V
R
I
K
K
D
P
Dog
Lupus familis
XP_849554
441
50086
G112
F
L
Q
L
L
Q
N
G
V
R
V
K
R
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BM81
407
46202
S78
F
F
C
F
L
Q
D
S
L
S
S
K
E
N
H
Rat
Rattus norvegicus
B2GV54
408
45803
S77
G
K
K
S
A
R
S
S
P
R
V
K
V
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519759
267
30056
Chicken
Gallus gallus
XP_001231394
476
51887
G147
F
G
R
Y
V
R
Q
G
R
R
L
R
L
D
P
Frog
Xenopus laevis
NP_001088517
361
40534
E37
L
M
V
G
K
L
G
E
D
P
K
L
F
I
K
Zebra Danio
Brachydanio rerio
NP_001166113
412
46251
T80
W
C
R
C
H
I
M
T
C
K
R
S
V
P
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.3
62.3
N.A.
62.4
31.6
N.A.
34.1
42.2
42
38.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
98.5
73
N.A.
78.8
50
N.A.
45.7
58.6
60.6
57.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
40
N.A.
40
20
N.A.
0
33.3
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
60
33.3
N.A.
0
60
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
10
10
10
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
40
0
10
0
0
0
0
50
10
% D
% Glu:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% E
% Phe:
60
10
0
40
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
10
10
0
10
0
0
10
20
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
30
0
0
0
0
0
0
0
0
20
% H
% Ile:
0
30
0
0
0
10
0
0
0
0
30
0
0
10
0
% I
% Lys:
0
10
10
0
10
0
0
0
0
10
10
60
30
0
10
% K
% Leu:
10
10
0
10
50
10
0
0
10
0
10
10
10
0
0
% L
% Met:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
40
% P
% Gln:
0
0
10
0
0
20
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
50
0
0
20
0
0
10
60
10
10
10
0
0
% R
% Ser:
0
0
0
10
0
0
10
50
0
10
10
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% T
% Val:
0
0
10
0
10
0
0
0
40
0
20
0
20
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _