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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDKAL1
All Species:
25.76
Human Site:
S421
Identified Species:
51.52
UniProt:
Q5VV42
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VV42
NP_060244.2
579
65111
S421
K
Q
R
T
K
D
L
S
R
V
F
H
S
Y
S
Chimpanzee
Pan troglodytes
XP_001171161
579
65092
S421
K
Q
R
T
K
D
L
S
R
V
F
H
S
Y
S
Rhesus Macaque
Macaca mulatta
XP_001098819
576
64700
S421
K
Q
R
T
K
D
L
S
W
V
F
H
S
Y
S
Dog
Lupus familis
XP_849433
578
65064
S420
K
Q
R
T
K
D
L
S
R
V
F
H
S
Y
N
Cat
Felis silvestris
Mouse
Mus musculus
Q91WE6
578
65270
S420
K
Q
R
T
K
D
L
S
R
V
F
H
S
Y
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514441
419
47092
R273
F
I
N
Q
F
Y
P
R
P
G
T
P
A
A
K
Chicken
Gallus gallus
XP_418914
583
65778
S420
K
Q
R
T
K
D
L
S
Q
L
F
H
S
Y
N
Frog
Xenopus laevis
Q6NS26
556
62888
K410
Q
V
L
A
H
V
K
K
R
R
T
K
E
L
S
Zebra Danio
Brachydanio rerio
Q6PG34
547
61920
Q401
G
T
P
A
A
L
M
Q
Q
L
P
A
H
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4W1
552
62615
N399
R
F
P
S
L
F
I
N
Q
F
F
P
R
P
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8MXQ7
425
48609
A279
V
E
A
R
K
R
T
A
A
M
S
E
L
F
R
Sea Urchin
Strong. purpuratus
XP_001188890
660
73411
T418
K
R
R
T
K
A
L
T
V
L
F
K
S
Y
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.2
91.7
N.A.
90.5
N.A.
N.A.
64.9
80.9
78.5
68.9
N.A.
57.5
N.A.
38.1
53.9
Protein Similarity:
100
100
98.6
95.1
N.A.
94.1
N.A.
N.A.
69.5
89.8
86.6
81.3
N.A.
71.8
N.A.
50.5
70.6
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
N.A.
N.A.
0
80
13.3
0
N.A.
6.6
N.A.
6.6
53.3
P-Site Similarity:
100
100
93.3
100
N.A.
100
N.A.
N.A.
6.6
100
20
20
N.A.
40
N.A.
33.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
17
9
9
0
9
9
0
0
9
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
0
0
0
0
0
9
9
0
0
% E
% Phe:
9
9
0
0
9
9
0
0
0
9
67
0
0
9
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
50
9
0
0
% H
% Ile:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
59
0
0
0
67
0
9
9
0
0
0
17
0
0
17
% K
% Leu:
0
0
9
0
9
9
59
0
0
25
0
0
9
9
0
% L
% Met:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
25
% N
% Pro:
0
0
17
0
0
0
9
0
9
0
9
17
0
9
0
% P
% Gln:
9
50
0
9
0
0
0
9
25
0
0
0
0
0
9
% Q
% Arg:
9
9
59
9
0
9
0
9
42
9
0
0
9
0
9
% R
% Ser:
0
0
0
9
0
0
0
50
0
0
9
0
59
0
34
% S
% Thr:
0
9
0
59
0
0
9
9
0
0
17
0
0
0
0
% T
% Val:
9
9
0
0
0
9
0
0
9
42
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
59
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _