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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDKAL1
All Species:
22.12
Human Site:
S501
Identified Species:
44.24
UniProt:
Q5VV42
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VV42
NP_060244.2
579
65111
S501
D
A
K
V
Y
T
P
S
I
S
K
P
L
A
K
Chimpanzee
Pan troglodytes
XP_001171161
579
65092
S501
D
A
K
V
Y
T
P
S
I
S
K
P
L
A
K
Rhesus Macaque
Macaca mulatta
XP_001098819
576
64700
S501
D
A
K
V
Y
T
P
S
I
S
K
P
L
A
K
Dog
Lupus familis
XP_849433
578
65064
S500
D
A
K
V
Y
T
P
S
I
S
K
P
L
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91WE6
578
65270
S500
E
T
R
V
Y
T
P
S
I
S
K
P
L
A
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514441
419
47092
M347
V
P
K
N
P
Q
F
M
G
K
M
V
E
V
D
Chicken
Gallus gallus
XP_418914
583
65778
S500
D
A
R
V
Y
T
A
S
I
T
R
P
L
A
K
Frog
Xenopus laevis
Q6NS26
556
62888
K484
E
A
G
K
H
F
M
K
G
Q
P
V
Q
D
S
Zebra Danio
Brachydanio rerio
Q6PG34
547
61920
Y475
K
M
V
Q
V
E
V
Y
E
C
G
K
H
Y
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4W1
552
62615
R474
E
Q
V
L
L
P
M
R
D
N
L
L
G
T
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8MXQ7
425
48609
P353
K
F
S
M
I
S
K
P
A
S
I
Q
E
D
Q
Sea Urchin
Strong. purpuratus
XP_001188890
660
73411
P498
V
G
P
A
R
N
I
P
V
Q
N
Q
Q
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.2
91.7
N.A.
90.5
N.A.
N.A.
64.9
80.9
78.5
68.9
N.A.
57.5
N.A.
38.1
53.9
Protein Similarity:
100
100
98.6
95.1
N.A.
94.1
N.A.
N.A.
69.5
89.8
86.6
81.3
N.A.
71.8
N.A.
50.5
70.6
P-Site Identity:
100
100
100
100
N.A.
80
N.A.
N.A.
6.6
73.3
6.6
0
N.A.
0
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
6.6
93.3
20
0
N.A.
26.6
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
9
0
0
9
0
9
0
0
0
0
59
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
42
0
0
0
0
0
0
0
9
0
0
0
0
17
9
% D
% Glu:
25
0
0
0
0
9
0
0
9
0
0
0
17
0
0
% E
% Phe:
0
9
0
0
0
9
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
0
0
0
0
0
17
0
9
0
9
0
9
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
9
0
9
0
50
0
9
0
0
0
0
% I
% Lys:
17
0
42
9
0
0
9
9
0
9
42
9
0
0
50
% K
% Leu:
0
0
0
9
9
0
0
0
0
0
9
9
50
0
0
% L
% Met:
0
9
0
9
0
0
17
9
0
0
9
0
0
0
9
% M
% Asn:
0
0
0
9
0
9
0
0
0
9
9
0
0
0
0
% N
% Pro:
0
9
9
0
9
9
42
17
0
0
9
50
0
0
0
% P
% Gln:
0
9
0
9
0
9
0
0
0
17
0
17
17
0
9
% Q
% Arg:
0
0
17
0
9
0
0
9
0
0
9
0
0
0
9
% R
% Ser:
0
0
9
0
0
9
0
50
0
50
0
0
0
0
9
% S
% Thr:
0
9
0
0
0
50
0
0
0
9
0
0
0
9
0
% T
% Val:
17
0
17
50
9
0
9
0
9
0
0
17
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
50
0
0
9
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _