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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDKAL1 All Species: 8.48
Human Site: S528 Identified Species: 16.97
UniProt: Q5VV42 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VV42 NP_060244.2 579 65111 S528 G L G N Q L S S G S H T S A A
Chimpanzee Pan troglodytes XP_001171161 579 65092 S528 G L G N Q L S S G S H T S A A
Rhesus Macaque Macaca mulatta XP_001098819 576 64700 H528 G L G S S G S H T S A A S Q C
Dog Lupus familis XP_849433 578 65064 S527 R P R S H L S S A R H P S A A
Cat Felis silvestris
Mouse Mus musculus Q91WE6 578 65270 G527 R L G N H P N G T S D T C P A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514441 419 47092 Y374 P V S E A Q V Y T P S I S T P
Chicken Gallus gallus XP_418914 583 65778 W527 A P R N G T K W K A H R S A E
Frog Xenopus laevis Q6NS26 556 62888 T511 K G E V S G L T E E L K P P N
Zebra Danio Brachydanio rerio Q6PG34 547 61920 L502 A Y T T A P L L K G Q V S G H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K4W1 552 62615 D501 M V G E I L D D E R D W T R C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q8MXQ7 425 48609 T380 V F C L V L I T L Y S V D R F
Sea Urchin Strong. purpuratus XP_001188890 660 73411 K525 R E S S S P I K A P L P W V S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.2 91.7 N.A. 90.5 N.A. N.A. 64.9 80.9 78.5 68.9 N.A. 57.5 N.A. 38.1 53.9
Protein Similarity: 100 100 98.6 95.1 N.A. 94.1 N.A. N.A. 69.5 89.8 86.6 81.3 N.A. 71.8 N.A. 50.5 70.6
P-Site Identity: 100 100 40 46.6 N.A. 40 N.A. N.A. 6.6 26.6 0 6.6 N.A. 13.3 N.A. 6.6 0
P-Site Similarity: 100 100 46.6 53.3 N.A. 46.6 N.A. N.A. 13.3 33.3 6.6 6.6 N.A. 26.6 N.A. 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 17 0 0 0 17 9 9 9 0 34 34 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 17 % C
% Asp: 0 0 0 0 0 0 9 9 0 0 17 0 9 0 0 % D
% Glu: 0 9 9 17 0 0 0 0 17 9 0 0 0 0 9 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 25 9 42 0 9 17 0 9 17 9 0 0 0 9 0 % G
% His: 0 0 0 0 17 0 0 9 0 0 34 0 0 0 9 % H
% Ile: 0 0 0 0 9 0 17 0 0 0 0 9 0 0 0 % I
% Lys: 9 0 0 0 0 0 9 9 17 0 0 9 0 0 0 % K
% Leu: 0 34 0 9 0 42 17 9 9 0 17 0 0 0 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 34 0 0 9 0 0 0 0 0 0 0 9 % N
% Pro: 9 17 0 0 0 25 0 0 0 17 0 17 9 17 9 % P
% Gln: 0 0 0 0 17 9 0 0 0 0 9 0 0 9 0 % Q
% Arg: 25 0 17 0 0 0 0 0 0 17 0 9 0 17 0 % R
% Ser: 0 0 17 25 25 0 34 25 0 34 17 0 59 0 9 % S
% Thr: 0 0 9 9 0 9 0 17 25 0 0 25 9 9 0 % T
% Val: 9 17 0 9 9 0 9 0 0 0 0 17 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 9 9 0 0 % W
% Tyr: 0 9 0 0 0 0 0 9 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _