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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDKAL1
All Species:
12.73
Human Site:
S533
Identified Species:
25.45
UniProt:
Q5VV42
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VV42
NP_060244.2
579
65111
S533
L
S
S
G
S
H
T
S
A
A
S
Q
C
D
S
Chimpanzee
Pan troglodytes
XP_001171161
579
65092
S533
L
S
S
G
S
H
T
S
A
A
S
Q
C
N
S
Rhesus Macaque
Macaca mulatta
XP_001098819
576
64700
S533
G
S
H
T
S
A
A
S
Q
C
D
S
A
S
S
Dog
Lupus familis
XP_849433
578
65064
S532
L
S
S
A
R
H
P
S
A
A
V
R
R
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91WE6
578
65270
C532
P
N
G
T
S
D
T
C
P
A
T
Q
H
G
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514441
419
47092
S379
Q
V
Y
T
P
S
I
S
T
P
L
A
K
G
E
Chicken
Gallus gallus
XP_418914
583
65778
S532
T
K
W
K
A
H
R
S
A
E
I
P
V
K
A
Frog
Xenopus laevis
Q6NS26
556
62888
P516
G
L
T
E
E
L
K
P
P
N
N
I
P
K
S
Zebra Danio
Brachydanio rerio
Q6PG34
547
61920
S507
P
L
L
K
G
Q
V
S
G
H
T
Q
A
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4W1
552
62615
T506
L
D
D
E
R
D
W
T
R
C
A
K
N
Q
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8MXQ7
425
48609
D385
L
I
T
L
Y
S
V
D
R
F
L
Y
P
G
F
Sea Urchin
Strong. purpuratus
XP_001188890
660
73411
W530
P
I
K
A
P
L
P
W
V
S
I
I
M
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.2
91.7
N.A.
90.5
N.A.
N.A.
64.9
80.9
78.5
68.9
N.A.
57.5
N.A.
38.1
53.9
Protein Similarity:
100
100
98.6
95.1
N.A.
94.1
N.A.
N.A.
69.5
89.8
86.6
81.3
N.A.
71.8
N.A.
50.5
70.6
P-Site Identity:
100
93.3
26.6
60
N.A.
33.3
N.A.
N.A.
6.6
20
6.6
13.3
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
100
26.6
66.6
N.A.
46.6
N.A.
N.A.
6.6
33.3
20
20
N.A.
26.6
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
9
9
9
0
34
34
9
9
17
9
9
% A
% Cys:
0
0
0
0
0
0
0
9
0
17
0
0
17
0
0
% C
% Asp:
0
9
9
0
0
17
0
9
0
0
9
0
0
17
0
% D
% Glu:
0
0
0
17
9
0
0
0
0
9
0
0
0
0
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% F
% Gly:
17
0
9
17
9
0
0
0
9
0
0
0
0
34
0
% G
% His:
0
0
9
0
0
34
0
0
0
9
0
0
9
0
0
% H
% Ile:
0
17
0
0
0
0
9
0
0
0
17
17
0
0
0
% I
% Lys:
0
9
9
17
0
0
9
0
0
0
0
9
9
17
0
% K
% Leu:
42
17
9
9
0
17
0
0
0
0
17
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
9
9
0
9
9
0
% N
% Pro:
25
0
0
0
17
0
17
9
17
9
0
9
17
0
0
% P
% Gln:
9
0
0
0
0
9
0
0
9
0
0
34
0
9
0
% Q
% Arg:
0
0
0
0
17
0
9
0
17
0
0
9
9
0
0
% R
% Ser:
0
34
25
0
34
17
0
59
0
9
17
9
0
9
50
% S
% Thr:
9
0
17
25
0
0
25
9
9
0
17
0
0
0
0
% T
% Val:
0
9
0
0
0
0
17
0
9
0
9
0
9
0
17
% V
% Trp:
0
0
9
0
0
0
9
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
9
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _