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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDKAL1
All Species:
13.03
Human Site:
S542
Identified Species:
26.06
UniProt:
Q5VV42
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VV42
NP_060244.2
579
65111
S542
A
S
Q
C
D
S
A
S
S
R
M
V
L
P
M
Chimpanzee
Pan troglodytes
XP_001171161
579
65092
S542
A
S
Q
C
N
S
A
S
S
R
M
V
L
P
M
Rhesus Macaque
Macaca mulatta
XP_001098819
576
64700
M542
C
D
S
A
S
S
R
M
V
L
P
M
P
R
L
Dog
Lupus familis
XP_849433
578
65064
S541
A
V
R
R
D
S
A
S
S
R
L
V
L
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91WE6
578
65270
Y541
A
T
Q
H
G
S
A
Y
S
R
M
V
L
Q
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514441
419
47092
S388
P
L
A
K
G
E
V
S
G
L
T
E
V
S
K
Chicken
Gallus gallus
XP_418914
583
65778
L541
E
I
P
V
K
A
P
L
I
P
W
M
A
L
H
Frog
Xenopus laevis
Q6NS26
556
62888
T525
N
N
I
P
K
S
E
T
L
L
E
K
H
W
E
Zebra Danio
Brachydanio rerio
Q6PG34
547
61920
E516
H
T
Q
A
G
V
C
E
P
Q
C
W
M
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4W1
552
62615
P515
C
A
K
N
Q
E
L
P
N
V
Q
V
Q
T
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8MXQ7
425
48609
E394
F
L
Y
P
G
F
F
E
E
W
L
P
F
L
A
Sea Urchin
Strong. purpuratus
XP_001188890
660
73411
I539
S
I
I
M
A
V
L
I
A
V
A
F
L
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.2
91.7
N.A.
90.5
N.A.
N.A.
64.9
80.9
78.5
68.9
N.A.
57.5
N.A.
38.1
53.9
Protein Similarity:
100
100
98.6
95.1
N.A.
94.1
N.A.
N.A.
69.5
89.8
86.6
81.3
N.A.
71.8
N.A.
50.5
70.6
P-Site Identity:
100
93.3
6.6
60
N.A.
66.6
N.A.
N.A.
6.6
0
6.6
13.3
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
100
20
80
N.A.
73.3
N.A.
N.A.
13.3
13.3
20
33.3
N.A.
26.6
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
9
9
17
9
9
34
0
9
0
9
0
9
0
9
% A
% Cys:
17
0
0
17
0
0
9
0
0
0
9
0
0
0
0
% C
% Asp:
0
9
0
0
17
0
0
0
0
0
0
0
0
9
9
% D
% Glu:
9
0
0
0
0
17
9
17
9
0
9
9
0
0
9
% E
% Phe:
9
0
0
0
0
9
9
0
0
0
0
9
9
0
0
% F
% Gly:
0
0
0
0
34
0
0
0
9
0
0
0
0
0
0
% G
% His:
9
0
0
9
0
0
0
0
0
0
0
0
9
9
9
% H
% Ile:
0
17
17
0
0
0
0
9
9
0
0
0
0
0
0
% I
% Lys:
0
0
9
9
17
0
0
0
0
0
0
9
0
0
9
% K
% Leu:
0
17
0
0
0
0
17
9
9
25
17
0
42
17
17
% L
% Met:
0
0
0
9
0
0
0
9
0
0
25
17
9
0
25
% M
% Asn:
9
9
0
9
9
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
9
0
9
17
0
0
9
9
9
9
9
9
9
25
0
% P
% Gln:
0
0
34
0
9
0
0
0
0
9
9
0
9
9
0
% Q
% Arg:
0
0
9
9
0
0
9
0
0
34
0
0
0
9
9
% R
% Ser:
9
17
9
0
9
50
0
34
34
0
0
0
0
9
0
% S
% Thr:
0
17
0
0
0
0
0
9
0
0
9
0
0
9
0
% T
% Val:
0
9
0
9
0
17
9
0
9
17
0
42
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
9
9
0
9
0
% W
% Tyr:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _