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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDKAL1
All Species:
31.52
Human Site:
Y297
Identified Species:
63.03
UniProt:
Q5VV42
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VV42
NP_060244.2
579
65111
Y297
L
G
M
T
N
P
P
Y
I
L
E
H
L
E
E
Chimpanzee
Pan troglodytes
XP_001171161
579
65092
Y297
L
G
M
T
N
P
P
Y
I
L
E
H
L
E
E
Rhesus Macaque
Macaca mulatta
XP_001098819
576
64700
Y297
L
G
M
T
N
P
P
Y
I
L
E
H
L
E
E
Dog
Lupus familis
XP_849433
578
65064
Y296
L
G
M
T
N
P
P
Y
I
L
E
H
L
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91WE6
578
65270
Y296
L
G
M
T
N
P
P
Y
I
L
E
H
L
E
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514441
419
47092
P159
W
K
L
V
E
V
I
P
E
G
A
M
L
R
L
Chicken
Gallus gallus
XP_418914
583
65778
Y296
L
G
M
T
N
P
P
Y
I
L
E
H
L
E
E
Frog
Xenopus laevis
Q6NS26
556
62888
Y293
L
G
M
T
N
P
P
Y
I
L
E
H
L
E
E
Zebra Danio
Brachydanio rerio
Q6PG34
547
61920
M287
G
A
M
L
R
L
G
M
T
N
P
P
Y
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4W1
552
62615
E280
D
I
G
S
S
L
P
E
L
L
W
Q
L
V
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8MXQ7
425
48609
E165
Y
I
L
D
H
L
E
E
I
A
E
I
L
N
H
Sea Urchin
Strong. purpuratus
XP_001188890
660
73411
Y294
I
G
M
T
N
P
P
Y
I
L
D
H
L
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.2
91.7
N.A.
90.5
N.A.
N.A.
64.9
80.9
78.5
68.9
N.A.
57.5
N.A.
38.1
53.9
Protein Similarity:
100
100
98.6
95.1
N.A.
94.1
N.A.
N.A.
69.5
89.8
86.6
81.3
N.A.
71.8
N.A.
50.5
70.6
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
6.6
100
100
6.6
N.A.
26.6
N.A.
20
80
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
13.3
100
100
6.6
N.A.
46.6
N.A.
33.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
9
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
9
17
9
0
67
0
0
67
67
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
67
9
0
0
0
9
0
0
9
0
0
0
0
9
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
67
0
0
9
% H
% Ile:
9
17
0
0
0
0
9
0
75
0
0
9
0
9
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
59
0
17
9
0
25
0
0
9
75
0
0
92
0
17
% L
% Met:
0
0
75
0
0
0
0
9
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
67
0
0
0
0
9
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
67
75
9
0
0
9
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% R
% Ser:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
67
0
0
0
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
9
0
9
0
0
0
0
0
0
0
9
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
67
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _