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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METTL11B All Species: 19.09
Human Site: S101 Identified Species: 32.31
UniProt: Q5VVY1 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VVY1 NP_001129579 283 32400 S101 S S P D I Q A S Q K F L R K F
Chimpanzee Pan troglodytes XP_520309 223 25269 R78 G I G R I T K R L L L P L F R
Rhesus Macaque Macaca mulatta XP_001093866 283 32445 S101 S S P D I Q A S R K F L R K F
Dog Lupus familis XP_547472 283 32180 S101 S N P D I Q S S R K F L R K F
Cat Felis silvestris
Mouse Mus musculus Q8R2U4 223 25402 R78 G I G R I T K R L L L P L F R
Rat Rattus norvegicus Q5BJX0 223 25446 R78 G I G R I T K R L L L P L F R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514588 353 38867 G157 A T G S E Y G G Q R Q G V I S
Chicken Gallus gallus XP_426622 363 42060 S101 S N I D I E S S R E F L R K F
Frog Xenopus laevis NP_001089614 223 25199 R78 G I G R I T K R L L L P L F K
Zebra Danio Brachydanio rerio XP_001923120 285 33086 S108 S D I D L E G S R Q F L K K F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623109 237 27478 F92 K N L L L N H F K H I D L V E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784765 226 25700 H81 G I G R I T K H L L L P L F Q
Poplar Tree Populus trichocarpa XP_002317082 276 31081 T100 G S G I G R I T K N L L I R F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38340 232 26049 A87 T M L H K H A A K I D L V E P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.9 97.5 95.4 N.A. 40.2 40.6 N.A. 43.6 59.2 40.6 60 N.A. N.A. 34.2 N.A. 33.9
Protein Similarity: 100 57.9 98.9 97.5 N.A. 58.2 58.2 N.A. 54.9 68.3 60.4 78.2 N.A. N.A. 51.5 N.A. 51.9
P-Site Identity: 100 6.6 93.3 80 N.A. 6.6 6.6 N.A. 6.6 60 6.6 46.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 6.6 100 100 N.A. 6.6 6.6 N.A. 26.6 93.3 6.6 80 N.A. N.A. 20 N.A. 6.6
Percent
Protein Identity: 31.4 N.A. N.A. N.A. 25.8 N.A.
Protein Similarity: 50.5 N.A. N.A. N.A. 42 N.A.
P-Site Identity: 20 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 46.6 N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 22 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 36 0 0 0 0 0 0 8 8 0 0 0 % D
% Glu: 0 0 0 0 8 15 0 0 0 8 0 0 0 8 8 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 36 0 0 36 43 % F
% Gly: 43 0 50 0 8 0 15 8 0 0 0 8 0 0 0 % G
% His: 0 0 0 8 0 8 8 8 0 8 0 0 0 0 0 % H
% Ile: 0 36 15 8 65 0 8 0 0 8 8 0 8 8 0 % I
% Lys: 8 0 0 0 8 0 36 0 22 22 0 0 8 36 8 % K
% Leu: 0 0 15 8 15 0 0 0 36 36 43 50 43 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 22 0 0 0 8 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 22 0 0 0 0 0 0 0 0 36 0 0 8 % P
% Gln: 0 0 0 0 0 22 0 0 15 8 8 0 0 0 8 % Q
% Arg: 0 0 0 36 0 8 0 29 29 8 0 0 29 8 22 % R
% Ser: 36 22 0 8 0 0 15 36 0 0 0 0 0 0 8 % S
% Thr: 8 8 0 0 0 36 0 8 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 15 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _