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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL11B
All Species:
21.82
Human Site:
Y42
Identified Species:
36.92
UniProt:
Q5VVY1
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VVY1
NP_001129579
283
32400
Y42
R
N
D
F
F
Q
S
Y
L
Y
L
L
E
K
I
Chimpanzee
Pan troglodytes
XP_520309
223
25269
Y19
F
Y
S
K
A
K
T
Y
W
K
Q
I
P
P
T
Rhesus Macaque
Macaca mulatta
XP_001093866
283
32445
Y42
R
N
D
F
F
Q
S
Y
L
Y
L
L
E
K
I
Dog
Lupus familis
XP_547472
283
32180
Y42
R
N
D
F
F
Q
S
Y
L
Y
L
L
E
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2U4
223
25402
Y19
F
Y
S
K
A
K
T
Y
W
K
Q
I
P
P
T
Rat
Rattus norvegicus
Q5BJX0
223
25446
Y19
F
Y
S
K
A
K
T
Y
W
K
Q
I
P
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514588
353
38867
G98
P
R
S
E
G
R
L
G
S
I
S
D
R
C
N
Chicken
Gallus gallus
XP_426622
363
42060
Y42
Q
N
D
F
F
Q
C
Y
L
Y
L
L
E
T
L
Frog
Xenopus laevis
NP_001089614
223
25199
Y19
F
Y
G
K
A
Q
N
Y
W
K
N
V
P
A
T
Zebra Danio
Brachydanio rerio
XP_001923120
285
33086
Y49
R
K
E
F
F
A
S
Y
L
Y
L
L
E
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623109
237
27478
P33
A
K
Y
W
E
H
V
P
A
T
V
D
G
M
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784765
226
25700
W22
Y
N
D
A
K
D
Y
W
K
D
I
P
A
T
V
Poplar Tree
Populus trichocarpa
XP_002317082
276
31081
W41
Y
R
D
G
V
A
Y
W
E
G
V
E
A
S
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38340
232
26049
V28
V
D
A
T
V
D
G
V
L
G
G
Y
G
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.9
97.5
95.4
N.A.
40.2
40.6
N.A.
43.6
59.2
40.6
60
N.A.
N.A.
34.2
N.A.
33.9
Protein Similarity:
100
57.9
98.9
97.5
N.A.
58.2
58.2
N.A.
54.9
68.3
60.4
78.2
N.A.
N.A.
51.5
N.A.
51.9
P-Site Identity:
100
6.6
100
100
N.A.
6.6
6.6
N.A.
0
73.3
13.3
73.3
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
26.6
100
100
N.A.
26.6
26.6
N.A.
6.6
86.6
26.6
86.6
N.A.
N.A.
20
N.A.
33.3
Percent
Protein Identity:
31.4
N.A.
N.A.
N.A.
25.8
N.A.
Protein Similarity:
50.5
N.A.
N.A.
N.A.
42
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
29
15
0
0
8
0
0
0
15
8
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% C
% Asp:
0
8
43
0
0
15
0
0
0
8
0
15
0
0
0
% D
% Glu:
0
0
8
8
8
0
0
0
8
0
0
8
36
8
0
% E
% Phe:
29
0
0
36
36
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
8
0
8
8
0
15
8
0
15
0
8
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
8
22
0
0
29
% I
% Lys:
0
15
0
29
8
22
0
0
8
29
0
0
0
22
0
% K
% Leu:
0
0
0
0
0
0
8
0
43
0
36
36
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
36
0
0
0
0
8
0
0
0
8
0
0
0
8
% N
% Pro:
8
0
0
0
0
0
0
8
0
0
0
8
29
22
0
% P
% Gln:
8
0
0
0
0
36
0
0
0
0
22
0
0
8
0
% Q
% Arg:
29
15
0
0
0
8
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
29
0
0
0
29
0
8
0
8
0
0
8
0
% S
% Thr:
0
0
0
8
0
0
22
0
0
8
0
0
0
15
29
% T
% Val:
8
0
0
0
15
0
8
8
0
0
15
8
0
0
15
% V
% Trp:
0
0
0
8
0
0
0
15
29
0
0
0
0
0
0
% W
% Tyr:
15
29
8
0
0
0
15
65
0
36
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _