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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL11B
All Species:
16.67
Human Site:
Y69
Identified Species:
28.21
UniProt:
Q5VVY1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VVY1
NP_001129579
283
32400
Y69
I
N
G
E
M
Q
F
Y
A
R
A
K
L
F
Y
Chimpanzee
Pan troglodytes
XP_520309
223
25269
R46
S
I
D
I
N
S
S
R
K
F
L
Q
R
F
L
Rhesus Macaque
Macaca mulatta
XP_001093866
283
32445
Y69
I
N
G
E
M
Q
F
Y
A
R
A
K
L
F
Y
Dog
Lupus familis
XP_547472
283
32180
Y69
I
N
G
E
M
Q
F
Y
A
R
A
K
L
F
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2U4
223
25402
R46
N
I
D
L
N
S
S
R
K
F
L
Q
R
F
L
Rat
Rattus norvegicus
Q5BJX0
223
25446
R46
N
I
D
L
N
S
S
R
K
F
L
Q
R
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514588
353
38867
D125
N
V
S
P
Q
K
R
D
E
V
P
R
F
I
R
Chicken
Gallus gallus
XP_426622
363
42060
Y69
I
N
G
E
M
Q
F
Y
A
R
A
K
H
F
Y
Frog
Xenopus laevis
NP_001089614
223
25199
K46
N
T
D
L
N
S
S
K
K
F
L
Q
R
F
L
Zebra Danio
Brachydanio rerio
XP_001923120
285
33086
Y76
I
K
G
E
K
Q
F
Y
Y
R
A
Q
N
F
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623109
237
27478
A60
G
S
T
K
F
L
K
A
L
F
E
L
E
N
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784765
226
25700
E49
E
D
I
N
G
S
L
E
F
L
K
P
F
L
T
Poplar Tree
Populus trichocarpa
XP_002317082
276
31081
G68
A
D
V
K
G
S
E
G
F
L
Q
T
L
L
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38340
232
26049
S55
N
F
L
R
K
L
K
S
R
M
L
P
Q
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.9
97.5
95.4
N.A.
40.2
40.6
N.A.
43.6
59.2
40.6
60
N.A.
N.A.
34.2
N.A.
33.9
Protein Similarity:
100
57.9
98.9
97.5
N.A.
58.2
58.2
N.A.
54.9
68.3
60.4
78.2
N.A.
N.A.
51.5
N.A.
51.9
P-Site Identity:
100
6.6
100
100
N.A.
6.6
6.6
N.A.
0
93.3
6.6
66.6
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
13.3
100
100
N.A.
13.3
13.3
N.A.
13.3
93.3
13.3
73.3
N.A.
N.A.
13.3
N.A.
6.6
Percent
Protein Identity:
31.4
N.A.
N.A.
N.A.
25.8
N.A.
Protein Similarity:
50.5
N.A.
N.A.
N.A.
42
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
8
29
0
36
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
29
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
36
0
0
8
8
8
0
8
0
8
8
0
% E
% Phe:
0
8
0
0
8
0
36
0
15
36
0
0
15
65
0
% F
% Gly:
8
0
36
0
15
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
36
22
8
8
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
8
0
15
15
8
15
8
29
0
8
29
0
0
0
% K
% Leu:
0
0
8
22
0
15
8
0
8
15
36
8
29
15
29
% L
% Met:
0
0
0
0
29
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
36
29
0
8
29
0
0
0
0
0
0
0
8
8
8
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
8
15
0
0
8
% P
% Gln:
0
0
0
0
8
36
0
0
0
0
8
36
8
0
0
% Q
% Arg:
0
0
0
8
0
0
8
22
8
36
0
8
29
0
8
% R
% Ser:
8
8
8
0
0
43
29
8
0
0
0
0
0
0
0
% S
% Thr:
0
8
8
0
0
0
0
0
0
0
0
8
0
0
8
% T
% Val:
0
8
8
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
36
8
0
0
0
0
0
36
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _