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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF12L2
All Species:
24.55
Human Site:
S257
Identified Species:
60
UniProt:
Q5VW00
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VW00
NP_001013650.1
463
50803
S257
V
E
A
I
P
R
A
S
T
N
P
S
N
R
K
Chimpanzee
Pan troglodytes
XP_529143
510
55813
S304
V
E
A
I
P
R
A
S
T
N
P
S
N
R
K
Rhesus Macaque
Macaca mulatta
XP_001089560
463
50773
S257
V
E
A
I
P
R
A
S
T
N
P
S
N
R
K
Dog
Lupus familis
XP_549235
578
63266
S372
M
E
T
I
P
R
S
S
T
S
P
S
N
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGW4
469
51604
T263
M
E
A
I
P
R
A
T
T
N
P
G
N
R
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3R7
427
47600
N219
L
K
D
I
P
K
E
N
T
N
P
D
N
C
K
Frog
Xenopus laevis
Q63ZP7
446
49593
S242
L
K
D
I
P
K
E
S
S
N
P
V
N
C
K
Zebra Danio
Brachydanio rerio
Q08BB3
482
53852
Y276
L
K
D
I
P
K
E
Y
T
H
P
Y
N
C
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396383
459
52162
T256
P
D
K
A
D
V
P
T
H
R
L
I
Q
P
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791553
435
48529
L239
E
S
I
F
P
V
L
L
R
S
S
E
K
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.4
98.9
70.9
N.A.
82
N.A.
N.A.
N.A.
60.4
57.6
55.3
N.A.
N.A.
39.7
N.A.
39.9
Protein Similarity:
100
71.7
99.3
74.7
N.A.
88.2
N.A.
N.A.
N.A.
73
74.3
69.2
N.A.
N.A.
57.8
N.A.
58.7
P-Site Identity:
100
100
100
73.3
N.A.
80
N.A.
N.A.
N.A.
46.6
46.6
40
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
N.A.
N.A.
N.A.
73.3
73.3
66.6
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
40
10
0
0
40
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% C
% Asp:
0
10
30
0
10
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
10
50
0
0
0
0
30
0
0
0
0
10
0
0
10
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% H
% Ile:
0
0
10
80
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
30
10
0
0
30
0
0
0
0
0
0
10
0
80
% K
% Leu:
30
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% L
% Met:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
60
0
0
80
0
0
% N
% Pro:
10
0
0
0
90
0
10
0
0
0
80
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
50
0
0
10
10
0
0
0
50
0
% R
% Ser:
0
10
0
0
0
0
10
50
10
20
10
40
0
10
0
% S
% Thr:
0
0
10
0
0
0
0
20
70
0
0
0
0
0
0
% T
% Val:
30
0
0
0
0
20
0
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _