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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF12L2
All Species:
16.06
Human Site:
S390
Identified Species:
39.26
UniProt:
Q5VW00
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VW00
NP_001013650.1
463
50803
S390
L
E
E
R
A
S
S
S
L
D
S
M
P
G
P
Chimpanzee
Pan troglodytes
XP_529143
510
55813
S437
L
E
E
R
A
S
S
S
L
D
S
M
P
G
P
Rhesus Macaque
Macaca mulatta
XP_001089560
463
50773
S390
L
E
E
R
A
S
A
S
L
D
S
T
P
G
P
Dog
Lupus familis
XP_549235
578
63266
S505
L
E
E
R
A
S
A
S
P
D
S
S
P
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGW4
469
51604
S396
L
E
E
R
A
S
A
S
P
D
S
F
L
G
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3R7
427
47600
A352
L
D
E
R
P
P
R
A
C
Y
G
Q
K
Q
K
Frog
Xenopus laevis
Q63ZP7
446
49593
C375
L
E
D
S
T
G
N
C
R
N
A
K
K
K
G
Zebra Danio
Brachydanio rerio
Q08BB3
482
53852
P409
L
D
G
P
S
S
T
P
G
G
Y
R
N
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396383
459
52162
N396
L
E
S
S
I
N
S
N
R
I
V
V
L
K
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791553
435
48529
K371
I
E
S
D
I
D
G
K
T
V
P
V
K
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.4
98.9
70.9
N.A.
82
N.A.
N.A.
N.A.
60.4
57.6
55.3
N.A.
N.A.
39.7
N.A.
39.9
Protein Similarity:
100
71.7
99.3
74.7
N.A.
88.2
N.A.
N.A.
N.A.
73
74.3
69.2
N.A.
N.A.
57.8
N.A.
58.7
P-Site Identity:
100
100
86.6
80
N.A.
66.6
N.A.
N.A.
N.A.
20
13.3
13.3
N.A.
N.A.
20
N.A.
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
73.3
N.A.
N.A.
N.A.
33.3
40
33.3
N.A.
N.A.
40
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
50
0
30
10
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% C
% Asp:
0
20
10
10
0
10
0
0
0
50
0
0
0
0
0
% D
% Glu:
0
80
60
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
10
0
0
10
10
0
10
10
10
0
0
50
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
20
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
10
30
20
10
% K
% Leu:
90
0
0
0
0
0
0
0
30
0
0
0
20
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% M
% Asn:
0
0
0
0
0
10
10
10
0
10
0
0
10
0
0
% N
% Pro:
0
0
0
10
10
10
0
10
20
0
10
0
40
0
40
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% Q
% Arg:
0
0
0
60
0
0
10
0
20
0
0
10
0
10
10
% R
% Ser:
0
0
20
20
10
60
30
50
0
0
50
10
0
0
0
% S
% Thr:
0
0
0
0
10
0
10
0
10
0
0
10
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
10
10
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _