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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF12L2
All Species:
10
Human Site:
T88
Identified Species:
24.44
UniProt:
Q5VW00
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.44
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VW00
NP_001013650.1
463
50803
T88
Q
R
L
P
E
L
L
T
E
R
Q
L
D
L
G
Chimpanzee
Pan troglodytes
XP_529143
510
55813
P128
R
S
A
P
P
L
P
P
L
P
P
R
F
A
P
Rhesus Macaque
Macaca mulatta
XP_001089560
463
50773
T88
Q
R
L
P
E
L
L
T
E
R
Q
L
D
L
G
Dog
Lupus familis
XP_549235
578
63266
R203
Q
K
L
P
E
L
L
R
E
R
E
L
A
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGW4
469
51604
R94
L
R
L
P
E
L
L
R
E
R
Q
L
T
L
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3R7
427
47600
H72
F
A
S
Q
W
L
N
H
R
Q
V
V
C
G
T
Frog
Xenopus laevis
Q63ZP7
446
49593
S75
C
T
L
P
S
I
L
S
E
R
E
F
H
L
G
Zebra Danio
Brachydanio rerio
Q08BB3
482
53852
R85
G
R
I
P
G
I
L
R
E
R
E
F
S
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396383
459
52162
K105
I
L
T
H
D
L
F
K
E
Y
S
V
S
L
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791553
435
48529
S89
I
F
A
S
E
W
I
S
D
H
Q
V
V
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.4
98.9
70.9
N.A.
82
N.A.
N.A.
N.A.
60.4
57.6
55.3
N.A.
N.A.
39.7
N.A.
39.9
Protein Similarity:
100
71.7
99.3
74.7
N.A.
88.2
N.A.
N.A.
N.A.
73
74.3
69.2
N.A.
N.A.
57.8
N.A.
58.7
P-Site Identity:
100
13.3
100
73.3
N.A.
80
N.A.
N.A.
N.A.
6.6
46.6
46.6
N.A.
N.A.
20
N.A.
26.6
P-Site Similarity:
100
20
100
86.6
N.A.
80
N.A.
N.A.
N.A.
20
66.6
66.6
N.A.
N.A.
33.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
20
0
0
0
0
0
0
0
0
0
10
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
10
0
0
0
20
0
0
% D
% Glu:
0
0
0
0
50
0
0
0
70
0
30
0
0
0
0
% E
% Phe:
10
10
0
0
0
0
10
0
0
0
0
20
10
0
0
% F
% Gly:
10
0
0
0
10
0
0
0
0
0
0
0
0
10
70
% G
% His:
0
0
0
10
0
0
0
10
0
10
0
0
10
0
0
% H
% Ile:
20
0
10
0
0
20
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
10
10
50
0
0
70
60
0
10
0
0
40
0
80
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
70
10
0
10
10
0
10
10
0
0
0
10
% P
% Gln:
30
0
0
10
0
0
0
0
0
10
40
0
0
0
0
% Q
% Arg:
10
40
0
0
0
0
0
30
10
60
0
10
0
0
0
% R
% Ser:
0
10
10
10
10
0
0
20
0
0
10
0
20
0
0
% S
% Thr:
0
10
10
0
0
0
0
20
0
0
0
0
10
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
30
10
0
0
% V
% Trp:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _