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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF12L2
All Species:
34.85
Human Site:
Y375
Identified Species:
85.19
UniProt:
Q5VW00
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VW00
NP_001013650.1
463
50803
Y375
G
H
G
S
L
L
F
Y
D
I
R
A
Q
K
F
Chimpanzee
Pan troglodytes
XP_529143
510
55813
Y422
G
H
G
S
L
L
F
Y
D
I
R
A
Q
K
F
Rhesus Macaque
Macaca mulatta
XP_001089560
463
50773
Y375
G
H
G
S
L
L
F
Y
D
I
R
A
Q
K
F
Dog
Lupus familis
XP_549235
578
63266
Y490
G
H
G
S
L
L
F
Y
D
I
R
A
Q
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGW4
469
51604
Y381
G
H
G
S
L
L
F
Y
D
I
R
A
Q
K
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3R7
427
47600
Y337
G
H
G
S
L
L
F
Y
D
I
R
A
Q
R
F
Frog
Xenopus laevis
Q63ZP7
446
49593
Y360
G
Q
G
A
L
L
F
Y
D
I
R
A
Q
R
F
Zebra Danio
Brachydanio rerio
Q08BB3
482
53852
Y394
G
Q
G
S
L
L
F
Y
D
I
R
A
Q
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396383
459
52162
Y381
G
L
G
M
M
F
F
Y
D
V
R
A
Q
K
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791553
435
48529
F356
G
Q
G
A
L
M
F
F
D
L
R
A
G
H
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.4
98.9
70.9
N.A.
82
N.A.
N.A.
N.A.
60.4
57.6
55.3
N.A.
N.A.
39.7
N.A.
39.9
Protein Similarity:
100
71.7
99.3
74.7
N.A.
88.2
N.A.
N.A.
N.A.
73
74.3
69.2
N.A.
N.A.
57.8
N.A.
58.7
P-Site Identity:
100
100
100
93.3
N.A.
100
N.A.
N.A.
N.A.
93.3
80
86.6
N.A.
N.A.
60
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
100
93.3
93.3
N.A.
N.A.
80
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
0
0
0
0
0
0
100
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
100
10
0
0
0
0
0
0
90
% F
% Gly:
100
0
100
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
60
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
80
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% K
% Leu:
0
10
0
0
90
80
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
10
10
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
30
0
0
0
0
0
0
0
0
0
0
90
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
100
0
0
40
0
% R
% Ser:
0
0
0
70
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
90
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _