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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF12L2
All Species:
12.42
Human Site:
Y78
Identified Species:
30.37
UniProt:
Q5VW00
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VW00
NP_001013650.1
463
50803
Y78
F
E
G
E
L
R
G
Y
A
V
Q
R
L
P
E
Chimpanzee
Pan troglodytes
XP_529143
510
55813
L118
S
R
Q
T
L
F
P
L
S
P
R
S
A
P
P
Rhesus Macaque
Macaca mulatta
XP_001089560
463
50773
Y78
F
E
G
E
L
R
G
Y
A
V
Q
R
L
P
E
Dog
Lupus familis
XP_549235
578
63266
Y193
S
E
G
E
L
R
G
Y
A
V
Q
K
L
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGW4
469
51604
Y84
F
E
G
D
L
R
S
Y
G
V
L
R
L
P
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3R7
427
47600
N62
E
F
H
L
G
T
L
N
K
V
F
A
S
Q
W
Frog
Xenopus laevis
Q63ZP7
446
49593
H65
Y
L
H
L
L
R
G
H
A
A
C
T
L
P
S
Zebra Danio
Brachydanio rerio
Q08BB3
482
53852
F75
F
Q
R
S
L
R
G
F
A
A
G
R
I
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396383
459
52162
F95
K
I
N
Q
E
Y
G
F
R
H
I
L
T
H
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791553
435
48529
I79
R
E
V
H
V
G
E
I
N
K
I
F
A
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.4
98.9
70.9
N.A.
82
N.A.
N.A.
N.A.
60.4
57.6
55.3
N.A.
N.A.
39.7
N.A.
39.9
Protein Similarity:
100
71.7
99.3
74.7
N.A.
88.2
N.A.
N.A.
N.A.
73
74.3
69.2
N.A.
N.A.
57.8
N.A.
58.7
P-Site Identity:
100
13.3
100
86.6
N.A.
73.3
N.A.
N.A.
N.A.
6.6
40
46.6
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
26.6
100
93.3
N.A.
80
N.A.
N.A.
N.A.
6.6
53.3
66.6
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
50
20
0
10
20
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
10
50
0
30
10
0
10
0
0
0
0
0
0
0
50
% E
% Phe:
40
10
0
0
0
10
0
20
0
0
10
10
0
0
0
% F
% Gly:
0
0
40
0
10
10
60
0
10
0
10
0
0
0
10
% G
% His:
0
0
20
10
0
0
0
10
0
10
0
0
0
10
0
% H
% Ile:
0
10
0
0
0
0
0
10
0
0
20
0
10
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
10
10
0
10
0
0
0
% K
% Leu:
0
10
0
20
70
0
10
10
0
0
10
10
50
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
10
0
0
0
70
10
% P
% Gln:
0
10
10
10
0
0
0
0
0
0
30
0
0
10
0
% Q
% Arg:
10
10
10
0
0
60
0
0
10
0
10
40
0
0
0
% R
% Ser:
20
0
0
10
0
0
10
0
10
0
0
10
10
10
10
% S
% Thr:
0
0
0
10
0
10
0
0
0
0
0
10
10
0
0
% T
% Val:
0
0
10
0
10
0
0
0
0
50
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
10
0
0
0
0
10
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _