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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGAP6 All Species: 8.48
Human Site: S116 Identified Species: 18.67
UniProt: Q5VW22 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VW22 NP_001071154 663 73127 S116 H V S A V R F S Q Q Y S L C S
Chimpanzee Pan troglodytes XP_001141446 439 48772
Rhesus Macaque Macaca mulatta XP_001082744 804 89081 A231 D V A Q K I V A T R K K Q Q L
Dog Lupus familis XP_848466 936 102470 S363 D Y S S S V P S T P S T S Q K
Cat Felis silvestris
Mouse Mus musculus Q8BXK8 857 94393 S284 D Y S S S V P S T P S T S Q K
Rat Rattus norvegicus Q8CGU4 1186 124419 S600 A S N G G H T S D Y S S S L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421880 1213 132309 T640 Y S S S V P S T P S T S Q K E
Frog Xenopus laevis Q6NRL1 864 95088 S287 S S V P S T P S T S Q K E L R
Zebra Danio Brachydanio rerio Q08CI4 339 38765
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NGC3 995 108026 Y377 E N N N I T K Y N P G A A N S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C6C3 776 87784 T147 F V S L K K N T R G D I V A E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.9 56 49.6 N.A. 52.1 29.6 N.A. N.A. 40 48 21.7 N.A. 29.5 N.A. N.A. N.A.
Protein Similarity: 100 63.9 66.6 58.1 N.A. 62.1 38.7 N.A. N.A. 46.6 59.4 34.5 N.A. 41.7 N.A. N.A. N.A.
P-Site Identity: 100 0 6.6 13.3 N.A. 13.3 13.3 N.A. N.A. 20 6.6 0 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 0 26.6 26.6 N.A. 26.6 20 N.A. N.A. 40 6.6 0 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 10 0 0 0 10 0 0 0 10 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 28 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 19 % E
% Phe: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 10 0 0 0 0 10 10 0 0 0 0 % G
% His: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 10 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 19 10 10 0 0 0 10 19 0 10 19 % K
% Leu: 0 0 0 10 0 0 0 0 0 0 0 0 10 19 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 19 10 0 0 10 0 10 0 0 0 0 10 0 % N
% Pro: 0 0 0 10 0 10 28 0 10 28 0 0 0 0 10 % P
% Gln: 0 0 0 10 0 0 0 0 10 10 10 0 19 28 0 % Q
% Arg: 0 0 0 0 0 10 0 0 10 10 0 0 0 0 10 % R
% Ser: 10 28 46 28 28 0 10 46 0 19 28 28 28 0 19 % S
% Thr: 0 0 0 0 0 19 10 19 37 0 10 19 0 0 0 % T
% Val: 0 28 10 0 19 19 10 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 19 0 0 0 0 0 10 0 10 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _