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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGAP6
All Species:
0.61
Human Site:
S327
Identified Species:
1.33
UniProt:
Q5VW22
Number Species:
10
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VW22
NP_001071154
663
73127
S327
K
W
P
S
L
A
T
S
A
C
T
P
I
S
S
Chimpanzee
Pan troglodytes
XP_001141446
439
48772
S109
T
S
A
C
A
P
I
S
S
S
K
S
N
G
L
Rhesus Macaque
Macaca mulatta
XP_001082744
804
89081
D442
L
H
I
S
P
N
S
D
T
G
L
G
D
S
V
Dog
Lupus familis
XP_848466
936
102470
D574
A
N
S
A
I
S
S
D
T
G
L
G
D
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXK8
857
94393
D495
A
N
S
A
I
S
S
D
T
G
L
G
D
S
V
Rat
Rattus norvegicus
Q8CGU4
1186
124419
L811
D
C
T
P
S
G
D
L
S
P
L
S
R
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421880
1213
132309
D851
A
N
S
G
I
S
S
D
T
G
L
G
D
S
V
Frog
Xenopus laevis
Q6NRL1
864
95088
D498
T
N
S
A
I
S
S
D
T
G
L
G
D
S
V
Zebra Danio
Brachydanio rerio
Q08CI4
339
38765
C8
M
G
N
T
V
S
C
C
V
S
P
S
G
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NGC3
995
108026
Q588
P
L
K
S
N
S
S
Q
Q
T
S
G
D
E
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C6C3
776
87784
R358
R
F
R
T
R
H
N
R
S
A
S
Q
G
S
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.9
56
49.6
N.A.
52.1
29.6
N.A.
N.A.
40
48
21.7
N.A.
29.5
N.A.
N.A.
N.A.
Protein Similarity:
100
63.9
66.6
58.1
N.A.
62.1
38.7
N.A.
N.A.
46.6
59.4
34.5
N.A.
41.7
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
13.3
6.6
N.A.
6.6
0
N.A.
N.A.
6.6
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
20
33.3
N.A.
33.3
6.6
N.A.
N.A.
26.6
33.3
26.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
0
10
28
10
10
0
0
10
10
0
0
0
0
0
% A
% Cys:
0
10
0
10
0
0
10
10
0
10
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
10
46
0
0
0
0
55
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
10
0
10
0
0
0
46
0
55
19
10
10
% G
% His:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
37
0
10
0
0
0
0
0
10
0
0
% I
% Lys:
10
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
10
10
0
0
10
0
0
10
0
0
55
0
0
0
19
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
37
10
0
10
10
10
0
0
0
0
0
10
0
0
% N
% Pro:
10
0
10
10
10
10
0
0
0
10
10
10
0
0
19
% P
% Gln:
0
0
0
0
0
0
0
10
10
0
0
10
0
0
0
% Q
% Arg:
10
0
10
0
10
0
0
10
0
0
0
0
10
0
0
% R
% Ser:
0
10
37
28
10
55
55
19
28
19
19
28
0
73
10
% S
% Thr:
19
0
10
19
0
0
10
0
46
10
10
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
46
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _