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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGAP6
All Species:
30.3
Human Site:
S422
Identified Species:
66.67
UniProt:
Q5VW22
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VW22
NP_001071154
663
73127
S422
I
Q
S
Q
I
L
A
S
L
Q
S
C
E
S
S
Chimpanzee
Pan troglodytes
XP_001141446
439
48772
S204
A
S
L
Q
S
C
E
S
S
K
S
K
S
Q
L
Rhesus Macaque
Macaca mulatta
XP_001082744
804
89081
S537
I
E
S
Q
I
L
A
S
L
Q
S
C
E
S
S
Dog
Lupus familis
XP_848466
936
102470
S669
I
E
S
Q
I
L
A
S
L
Q
S
C
E
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXK8
857
94393
S590
I
E
S
Q
I
L
A
S
L
Q
S
C
E
S
S
Rat
Rattus norvegicus
Q8CGU4
1186
124419
S906
I
E
S
Q
I
L
A
S
L
Q
C
C
E
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421880
1213
132309
S946
I
E
S
Q
I
L
A
S
L
Q
S
C
E
S
S
Frog
Xenopus laevis
Q6NRL1
864
95088
S593
I
E
S
Q
I
L
A
S
L
Q
S
C
E
S
S
Zebra Danio
Brachydanio rerio
Q08CI4
339
38765
T103
K
K
Y
S
S
C
S
T
I
F
I
D
D
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NGC3
995
108026
K683
A
V
E
Q
E
I
F
K
S
L
Q
S
I
E
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C6C3
776
87784
L453
P
A
T
E
N
L
T
L
N
Q
K
E
D
Y
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.9
56
49.6
N.A.
52.1
29.6
N.A.
N.A.
40
48
21.7
N.A.
29.5
N.A.
N.A.
N.A.
Protein Similarity:
100
63.9
66.6
58.1
N.A.
62.1
38.7
N.A.
N.A.
46.6
59.4
34.5
N.A.
41.7
N.A.
N.A.
N.A.
P-Site Identity:
100
20
93.3
93.3
N.A.
93.3
86.6
N.A.
N.A.
93.3
93.3
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
93.3
N.A.
N.A.
100
100
46.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
0
0
0
0
64
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
19
0
0
0
0
10
64
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
19
0
0
% D
% Glu:
0
55
10
10
10
0
10
0
0
0
0
10
64
10
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
64
0
0
0
64
10
0
0
10
0
10
0
10
0
0
% I
% Lys:
10
10
0
0
0
0
0
10
0
10
10
10
0
0
0
% K
% Leu:
0
0
10
0
0
73
0
10
64
10
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
10
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
82
0
0
0
0
0
73
10
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
64
10
19
0
10
73
19
0
64
10
10
73
73
% S
% Thr:
0
0
10
0
0
0
10
10
0
0
0
0
0
0
10
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _