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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGAP6 All Species: 1.52
Human Site: T361 Identified Species: 3.33
UniProt: Q5VW22 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VW22 NP_001071154 663 73127 T361 F S P S I S S T T S P K L N P
Chimpanzee Pan troglodytes XP_001141446 439 48772 N143 S T T S P K L N P P P S P H A
Rhesus Macaque Macaca mulatta XP_001082744 804 89081 H476 P H A N R K K H R R K K S T S
Dog Lupus familis XP_848466 936 102470 H608 P H A N R K K H R R K K S T S
Cat Felis silvestris
Mouse Mus musculus Q8BXK8 857 94393 H529 P H A N R K K H R R K K S T S
Rat Rattus norvegicus Q8CGU4 1186 124419 A845 T E G S A V Q A E A K R K M W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421880 1213 132309 H885 P H A N R K K H R R K K S T S
Frog Xenopus laevis Q6NRL1 864 95088 H532 P H A N R K K H R R K K S T S
Zebra Danio Brachydanio rerio Q08CI4 339 38765 Q42 D D T G P Y L Q H I S D R E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NGC3 995 108026 T622 G N K L E A Q T P N V K K R H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C6C3 776 87784 I392 D L R L C F R I I S P Q K T Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.9 56 49.6 N.A. 52.1 29.6 N.A. N.A. 40 48 21.7 N.A. 29.5 N.A. N.A. N.A.
Protein Similarity: 100 63.9 66.6 58.1 N.A. 62.1 38.7 N.A. N.A. 46.6 59.4 34.5 N.A. 41.7 N.A. N.A. N.A.
P-Site Identity: 100 13.3 6.6 6.6 N.A. 6.6 6.6 N.A. N.A. 6.6 6.6 0 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 26.6 13.3 13.3 N.A. 13.3 20 N.A. N.A. 13.3 13.3 0 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 46 0 10 10 0 10 0 10 0 0 0 0 10 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 19 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 10 0 0 10 0 0 0 10 0 0 0 0 10 0 % E
% Phe: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 46 0 0 0 0 0 46 10 0 0 0 0 10 10 % H
% Ile: 0 0 0 0 10 0 0 10 10 10 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 55 46 0 0 0 55 64 28 0 0 % K
% Leu: 0 10 0 19 0 0 19 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 10 0 46 0 0 0 10 0 10 0 0 0 10 0 % N
% Pro: 46 0 10 0 19 0 0 0 19 10 28 0 10 0 10 % P
% Gln: 0 0 0 0 0 0 19 10 0 0 0 10 0 0 0 % Q
% Arg: 0 0 10 0 46 0 10 0 46 46 0 10 10 10 0 % R
% Ser: 10 10 0 28 0 10 10 0 0 19 10 10 46 0 46 % S
% Thr: 10 10 19 0 0 0 0 19 10 0 0 0 0 55 0 % T
% Val: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _