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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPLAD2
All Species:
17.27
Human Site:
S216
Identified Species:
34.55
UniProt:
Q5VWC8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VWC8
NP_001010915.2
232
27520
S216
F
T
Y
S
H
L
Y
S
E
R
R
D
I
L
G
Chimpanzee
Pan troglodytes
XP_001148626
232
27515
S216
F
T
Y
S
H
L
Y
S
E
R
R
D
I
L
G
Rhesus Macaque
Macaca mulatta
XP_001099778
387
44871
S371
F
T
Y
S
H
L
Y
S
E
R
R
D
I
L
G
Dog
Lupus familis
XP_854086
229
27291
S213
Y
T
Y
S
H
L
Y
S
E
R
R
D
V
L
R
Cat
Felis silvestris
Mouse
Mus musculus
A2AKM2
232
27217
T216
F
T
Y
S
H
L
Y
T
E
R
K
D
F
L
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513582
415
47969
L397
M
Y
F
I
S
S
H
L
Y
S
E
R
K
T
S
Chicken
Gallus gallus
Q5ZM57
362
42817
L346
L
F
V
N
F
R
Y
L
Y
K
Q
R
K
Q
H
Frog
Xenopus laevis
Q6GNB5
218
25718
R211
E
R
K
Q
Y
F
Q
R
K
L
K
L
K
K
N
Zebra Danio
Brachydanio rerio
Q7SY06
359
42393
L343
L
F
I
N
F
R
H
L
F
K
Q
R
T
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396529
301
36122
R282
F
M
Y
M
L
M
S
R
M
N
Q
I
R
Y
K
Nematode Worm
Caenorhab. elegans
P24890
370
42564
P266
M
S
P
V
H
I
V
P
E
W
Y
F
L
F
A
Sea Urchin
Strong. purpuratus
XP_001196941
377
44119
M354
A
P
T
L
L
S
H
M
W
R
L
R
K
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
59.4
92.6
N.A.
85.3
N.A.
N.A.
46.9
28.1
56.9
29.2
N.A.
N.A.
26.9
20.5
21.4
Protein Similarity:
100
100
59.6
96.5
N.A.
90.5
N.A.
N.A.
49.4
43.6
68.9
43.7
N.A.
N.A.
45.8
34
37.4
P-Site Identity:
100
100
100
80
N.A.
73.3
N.A.
N.A.
0
6.6
0
0
N.A.
N.A.
13.3
13.3
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
N.A.
N.A.
13.3
26.6
20
26.6
N.A.
N.A.
26.6
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
42
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
50
0
9
0
0
0
0
% E
% Phe:
42
17
9
0
17
9
0
0
9
0
0
9
9
9
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% G
% His:
0
0
0
0
50
0
25
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
9
9
0
9
0
0
0
0
0
9
25
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
9
17
17
0
34
17
17
% K
% Leu:
17
0
0
9
17
42
0
25
0
9
9
9
9
42
0
% L
% Met:
17
9
0
9
0
9
0
9
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
17
0
0
0
0
0
9
0
0
0
0
9
% N
% Pro:
0
9
9
0
0
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
9
0
0
0
25
0
0
9
0
% Q
% Arg:
0
9
0
0
0
17
0
17
0
50
34
34
9
9
25
% R
% Ser:
0
9
0
42
9
17
9
34
0
9
0
0
0
0
9
% S
% Thr:
0
42
9
0
0
0
0
9
0
0
0
0
9
9
0
% T
% Val:
0
0
9
9
0
0
9
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% W
% Tyr:
9
9
50
0
9
0
50
0
17
0
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _