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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPLAD2
All Species:
23.03
Human Site:
T179
Identified Species:
46.06
UniProt:
Q5VWC8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VWC8
NP_001010915.2
232
27520
T179
P
Y
F
E
S
F
G
T
Y
S
T
K
L
P
F
Chimpanzee
Pan troglodytes
XP_001148626
232
27515
T179
P
Y
F
E
S
F
G
T
Y
S
T
K
L
P
F
Rhesus Macaque
Macaca mulatta
XP_001099778
387
44871
T334
P
Y
F
E
S
F
G
T
Y
S
T
K
L
P
F
Dog
Lupus familis
XP_854086
229
27291
T176
P
Y
F
E
S
F
G
T
Y
S
T
K
L
P
F
Cat
Felis silvestris
Mouse
Mus musculus
A2AKM2
232
27217
T179
P
Y
F
E
S
F
G
T
N
S
T
V
L
P
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513582
415
47969
T360
P
Y
F
E
S
F
G
T
Y
S
I
K
L
P
F
Chicken
Gallus gallus
Q5ZM57
362
42817
K309
P
I
F
S
E
T
G
K
F
S
L
G
L
P
N
Frog
Xenopus laevis
Q6GNB5
218
25718
S174
F
K
M
A
L
P
V
S
L
S
F
H
F
P
Y
Zebra Danio
Brachydanio rerio
Q7SY06
359
42393
L306
P
I
F
D
E
T
K
L
L
S
I
P
L
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396529
301
36122
K245
P
Y
F
E
E
T
Q
K
F
T
I
S
L
P
N
Nematode Worm
Caenorhab. elegans
P24890
370
42564
I229
L
G
K
D
A
Y
N
I
V
I
W
L
L
F
I
Sea Urchin
Strong. purpuratus
XP_001196941
377
44119
M317
P
F
Y
K
E
T
D
M
F
S
V
H
L
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
59.4
92.6
N.A.
85.3
N.A.
N.A.
46.9
28.1
56.9
29.2
N.A.
N.A.
26.9
20.5
21.4
Protein Similarity:
100
100
59.6
96.5
N.A.
90.5
N.A.
N.A.
49.4
43.6
68.9
43.7
N.A.
N.A.
45.8
34
37.4
P-Site Identity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
93.3
40
13.3
33.3
N.A.
N.A.
40
6.6
26.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
93.3
46.6
26.6
40
N.A.
N.A.
53.3
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
17
0
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
59
34
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
9
9
75
0
0
50
0
0
25
0
9
0
9
9
50
% F
% Gly:
0
9
0
0
0
0
59
0
0
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% H
% Ile:
0
17
0
0
0
0
0
9
0
9
25
0
0
0
9
% I
% Lys:
0
9
9
9
0
0
9
17
0
0
0
42
0
0
9
% K
% Leu:
9
0
0
0
9
0
0
9
17
0
9
9
92
0
0
% L
% Met:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
25
% N
% Pro:
84
0
0
0
0
9
0
0
0
0
0
9
0
92
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
9
50
0
0
9
0
84
0
9
0
0
0
% S
% Thr:
0
0
0
0
0
34
0
50
0
9
42
0
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
9
0
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
59
9
0
0
9
0
0
42
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _