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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPLAD2
All Species:
24.85
Human Site:
Y173
Identified Species:
49.7
UniProt:
Q5VWC8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VWC8
NP_001010915.2
232
27520
Y173
A
I
Y
Q
S
L
P
Y
F
E
S
F
G
T
Y
Chimpanzee
Pan troglodytes
XP_001148626
232
27515
Y173
A
I
Y
Q
S
L
P
Y
F
E
S
F
G
T
Y
Rhesus Macaque
Macaca mulatta
XP_001099778
387
44871
Y328
A
I
Y
Q
S
L
P
Y
F
E
S
F
G
T
Y
Dog
Lupus familis
XP_854086
229
27291
Y170
A
I
Y
Q
S
L
P
Y
F
E
S
F
G
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
A2AKM2
232
27217
Y173
T
I
Y
Q
S
L
P
Y
F
E
S
F
G
T
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513582
415
47969
Y354
A
I
Y
Q
S
L
P
Y
F
E
S
F
G
T
Y
Chicken
Gallus gallus
Q5ZM57
362
42817
I303
C
L
I
Q
S
I
P
I
F
S
E
T
G
K
F
Frog
Xenopus laevis
Q6GNB5
218
25718
K168
S
L
G
T
Y
S
F
K
M
A
L
P
V
S
L
Zebra Danio
Brachydanio rerio
Q7SY06
359
42393
I300
A
V
I
Q
S
I
P
I
F
D
E
T
K
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396529
301
36122
Y239
I
I
L
R
N
I
P
Y
F
E
E
T
Q
K
F
Nematode Worm
Caenorhab. elegans
P24890
370
42564
G223
C
F
S
P
E
Y
L
G
K
D
A
Y
N
I
V
Sea Urchin
Strong. purpuratus
XP_001196941
377
44119
F311
V
V
C
L
A
I
P
F
Y
K
E
T
D
M
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
59.4
92.6
N.A.
85.3
N.A.
N.A.
46.9
28.1
56.9
29.2
N.A.
N.A.
26.9
20.5
21.4
Protein Similarity:
100
100
59.6
96.5
N.A.
90.5
N.A.
N.A.
49.4
43.6
68.9
43.7
N.A.
N.A.
45.8
34
37.4
P-Site Identity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
100
33.3
0
33.3
N.A.
N.A.
33.3
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
100
53.3
20
53.3
N.A.
N.A.
60
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
0
9
0
0
0
0
9
9
0
0
0
0
% A
% Cys:
17
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
17
0
0
9
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
59
34
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
9
9
75
0
0
50
0
0
25
% F
% Gly:
0
0
9
0
0
0
0
9
0
0
0
0
59
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
59
17
0
0
34
0
17
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
9
9
9
0
0
9
17
0
% K
% Leu:
0
17
9
9
0
50
9
0
0
0
9
0
0
9
17
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
9
% N
% Pro:
0
0
0
9
0
0
84
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
67
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
9
0
67
9
0
0
0
9
50
0
0
9
0
% S
% Thr:
9
0
0
9
0
0
0
0
0
0
0
34
0
50
0
% T
% Val:
9
17
0
0
0
0
0
0
0
0
0
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
50
0
9
9
0
59
9
0
0
9
0
0
42
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _