Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTPLAD2 All Species: 28.79
Human Site: Y19 Identified Species: 57.58
UniProt: Q5VWC8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VWC8 NP_001010915.2 232 27520 Y19 P R Y R K N A Y L F I Y Y L I
Chimpanzee Pan troglodytes XP_001148626 232 27515 Y19 P R Y R K N A Y L F I Y Y L I
Rhesus Macaque Macaca mulatta XP_001099778 387 44871 Y174 P R Y R K N A Y L F I Y Y L I
Dog Lupus familis XP_854086 229 27291 Y16 P R Y R K S T Y L F I Y Y L I
Cat Felis silvestris
Mouse Mus musculus A2AKM2 232 27217 Y19 P R Y R K N V Y L F I Y Y L I
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513582 415 47969 Y200 D R Y R M N T Y L F I Y Y L I
Chicken Gallus gallus Q5ZM57 362 42817 Y149 F K H L K K G Y L I M Y N L V
Frog Xenopus laevis Q6GNB5 218 25718 H16 Y L I Q F C G H S W I F T N M
Zebra Danio Brachydanio rerio Q7SY06 359 42393 F146 F L G L K K G F L F M Y N L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396529 301 36122 Y85 K E D F K K V Y L I I Y N L C
Nematode Worm Caenorhab. elegans P24890 370 42564 F60 T P D S L M A F S T V Q Y I M
Sea Urchin Strong. purpuratus XP_001196941 377 44119 Y157 Y Q D I K N V Y L F M Y N L I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 59.4 92.6 N.A. 85.3 N.A. N.A. 46.9 28.1 56.9 29.2 N.A. N.A. 26.9 20.5 21.4
Protein Similarity: 100 100 59.6 96.5 N.A. 90.5 N.A. N.A. 49.4 43.6 68.9 43.7 N.A. N.A. 45.8 34 37.4
P-Site Identity: 100 100 100 86.6 N.A. 93.3 N.A. N.A. 80 33.3 6.6 33.3 N.A. N.A. 40 13.3 53.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 N.A. N.A. 80 60 40 53.3 N.A. N.A. 40 40 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 34 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 9 % C
% Asp: 9 0 25 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 17 0 0 9 9 0 0 17 0 67 0 9 0 0 0 % F
% Gly: 0 0 9 0 0 0 25 0 0 0 0 0 0 0 0 % G
% His: 0 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 9 0 0 0 0 0 17 67 0 0 9 59 % I
% Lys: 9 9 0 0 75 25 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 17 0 17 9 0 0 0 84 0 0 0 0 84 0 % L
% Met: 0 0 0 0 9 9 0 0 0 0 25 0 0 0 17 % M
% Asn: 0 0 0 0 0 50 0 0 0 0 0 0 34 9 0 % N
% Pro: 42 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 9 0 0 0 0 0 0 0 9 0 0 0 % Q
% Arg: 0 50 0 50 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 9 0 9 0 0 17 0 0 0 0 0 0 % S
% Thr: 9 0 0 0 0 0 17 0 0 9 0 0 9 0 0 % T
% Val: 0 0 0 0 0 0 25 0 0 0 9 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 17 0 50 0 0 0 0 75 0 0 0 84 59 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _