KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRAMEF16
All Species:
9.09
Human Site:
S206
Identified Species:
40
UniProt:
Q5VWM1
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VWM1
NP_001038945.1
474
54838
S206
L
K
R
V
Y
P
D
S
I
Q
E
L
E
I
K
Chimpanzee
Pan troglodytes
XP_001147639
474
54614
S206
L
K
R
V
Y
P
D
S
I
Q
E
L
E
I
K
Rhesus Macaque
Macaca mulatta
XP_001106552
474
54372
S206
L
E
R
I
Y
P
D
S
I
Q
E
L
E
V
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC16
493
54950
V189
R
E
A
L
Q
S
S
V
A
S
P
L
R
L
C
Rat
Rattus norvegicus
Q569B5
493
54896
R228
C
L
R
R
I
D
L
R
F
N
N
L
G
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q640Z9
509
57042
V238
E
L
L
N
P
G
S
V
R
Q
I
D
L
R
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.1
90
N.A.
N.A.
23.3
23.3
N.A.
N.A.
N.A.
22.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.4
94
N.A.
N.A.
40.9
41.5
N.A.
N.A.
N.A.
42
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
73.3
N.A.
N.A.
6.6
13.3
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
26.6
26.6
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
0
0
0
17
0
0
0
0
0
0
% A
% Cys:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% C
% Asp:
0
0
0
0
0
17
50
0
0
0
0
17
0
0
0
% D
% Glu:
17
34
0
0
0
0
0
0
0
0
50
0
50
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
17
% F
% Gly:
0
0
0
0
0
17
0
0
0
0
0
0
17
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
17
17
0
0
0
50
0
17
0
0
34
0
% I
% Lys:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
34
% K
% Leu:
50
34
17
17
0
0
17
0
0
0
0
84
17
34
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
17
0
0
0
0
0
17
17
0
0
0
0
% N
% Pro:
0
0
0
0
17
50
0
0
0
0
17
0
0
0
0
% P
% Gln:
0
0
0
0
17
0
0
0
0
67
0
0
0
0
0
% Q
% Arg:
17
0
67
17
0
0
0
17
17
0
0
0
17
17
34
% R
% Ser:
0
0
0
0
0
17
34
50
0
17
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
34
0
0
0
34
0
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _